Search Results - "cell adhesion"

The miracle of morphogenesis cell adhesion, polarity and cytoskeletal regulation /

Table of Contents: “…Contents: Self-assembly of cells into tissues and organs -- Understanding this process from the molecular to whole animal level -- Different cell types -- Cell adhesion -- Epithelial sheets -- Drosophila cell adhesion -- Gastrulation -- Cadherin expression -- Normal cell behavior and human disease -- Abelson tyrosine kinase -- Ena and Abl -- How does Abl function during more complex events of morphogenesis -- Other actin regulators -- Dorsal closure -- Cells use "landmarks" to establish and elaborate polarity -- Adherens junctions -- Drosophila cellularization -- Bazooka.…”
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Structure and function of adhesion GPCRs and their ligands

Subjects: “…Cell adhesion molecules. 91411…”
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EGF-TM7 receptors

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Adhesion GPCRs in nervous system development and disease

Subjects: “…Cell adhesion molecules. 92100…”
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Mechanisms of natural killer cell cytotoxicity

Table of Contents: “…Contents: Natural killer (NK) cells can kill infected or transformed cells -- Cytotoxic activity and target cell adhesion -- Integrin mediation -- Immunological synapse formation -- Cell apoptosis via lytic granule exocytosis -- NK cell expression of FasL or TRAIL -- Death receptor-mediated apoptosis -- Single force cell spectroscopy -- Granzyme B -- Caspase 8.…”
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The role of basophils in allergy

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Vascular cell signaling by membrane estrogen receptors

Table of Contents: “…Contents: Endothelium -- Endothelial dysfunction -- Estrogen-mediated cardiovascular protection and leukocyte-endothelial cell adhesion -- Estrogen as a determinant of cardiovascular risk -- Effects of estrogen on the cardiovascular system -- Rapid EC activation effects of estrogen -- Effect of estradiol on NO release from human endothelial cells -- Estrogen receptor knockout (ERKO) mouse cardiovascular studies -- Palmitoylation is required for membrane translocation of ER46 -- Akt/protein kinase B -- Endothelial homeostasis -- Kronos early estrogen prevention study.…”
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Roles of glycans in yeast cell walls

Table of Contents: “…Contents: The overall architecture of yeast cell walls and the roles of glycans -- Structure and biosynthesis of major cell wall components -- A scheme for cell wall assembly and crosslinking -- Cell wall dynamics in growth, budding, stress response, cell adhesion, and mating -- Cell wall structure in other fungi and a relationship among eukaryotic extracellular matrices.…”
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CD44 genetic deletion enhances and CD44 antibody targeting attenuates autoimmune inflammation

Table of Contents: “…Contents: CD44 and RHAMM (receptor for hyaluronan-mediated motility) are cell adhesion and cell homing receptors -- Cell migration -- Generation of different CD44 isoforms -- RHAMM also supports cell motility and is engaged in intracellular signalling -- Collagen-induced arthritis and type 1 diabetes are CD44-dependent pathologies -- Molecular redundancy -- CD44 targeting by anti-CD44 mAb may eradicate not only malignant cells and destructive inflammatory cells but also CD44-expressing normal cells which are committed to physiological functions.…”
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NK cell signaling to cytotoxicity parts 2 & 3 /

Table of Contents: “…Contents: Regulation of killing by the NKG2D/DAP10 receptor complex -- PI3K pathway regulates cell adhesion and MTOC polarization through a CrkL-Rap1 activation -- Grb2/Vav1 pathway regulates SLP-76 and PLCγ2 activation, calcium signaling and cell-mediated killing -- Inhibitory signaling from killer immunoglobulin receptors that recruit the tyrosine phosphatase SHP1 -- SHP1 targets.…”
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Pleiotropic and epistatic genes in sickle cell anemia

Table of Contents: “…Contents: Determination of pleiotropic genes -- Search for polymorphic genes among the pleiotropic genes as candidates for epistasis -- Known epistatic effects -- Kidney pathology in sickle cell disease -- Renal disease epidemiology -- Panoply of transgenic mice -- Involvement of metabolic pathways in constitutive chronic kidney damage in Tx mice -- Hypoxia -- Mediators of oxidative stress -- Up and down regulated genes -- HO- 1 histopathology -- The effect of sickle red blood cell adhesion on gene expression in PAF pre-treated microcirculatory bed -- Von Willebrand factor (vWF) and sickle cell anemia -- vWF, shear stress and sickle cell anaemia -- Epistatic genes may open new therapeutic strategies for SS disease -- PAF induces the up-regulation of a number of genes that have the capacity of protecting the endothelium, stem cells and other hematopoetic precursors.…”
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The Eph receptor family

Table of Contents: “…Contents: Members of the Eph receptor and ephrin ligand families and specificity of binding interactions -- Domain structure of Eph receptors and ephrins -- Eph receptor-ephrin interactions -- Dimerization, tetramerization and further clustering in Eph-ephrin signaling -- Tyrosine phosphorylation in Eph-ephrin activation -- Modes of signal termination -- Eph-ephrin signaling pathways affecting the actin cytoskeleton and cell adhesion: Cell repulsion versus adhesion/attraction, pathways that are activated downstream of Eph receptors -- Main Eph effects on cell behavior: shaping and positioning cellular processes and cell migration -- Eph receptors in topographic mapping in the visual system -- Eph receptors in the organization of axonal projections -- Eph receptors in angiogenesis and lymphangiogenesis -- Eph receptors in stem cell proliferation and differentiation -- Eph receptors in cancer -- Eph receptors as drug targets.…”
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LKB1 pathway and its role in cancer

Table of Contents: “…Contents: Mutations in LKB1 kinase cause Peutz Jeghers cancer syndrome -- LKB1-activation and effects -- LKB1/AMPK signaling pathway inhibits mTOR -- Evaluating the role of LKB1 in regulating PTEN-induced tumourigenesis -- AMPK-activators-mechanisms of action -- AMPK-activators delay tumor onset in mice -- Metformin as a useful drug in cancer prevention -- The LKB1:STRAD:MO25 complex -- Potential evolution of a pseudokinase -- LKB activation by STRAD and MO25 -- Location of LKB1 cancer mutations -- Activating protein kinases as a key challenge -- Analysis of the NUAK protein kinase -- Studying the role LKB1/NUAK1 signaling pathway in regulating cell adhesiveness and migration -- Modeling the novel LKB1.…”
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