Search Results - "amplifier"

Vesicular release of transmitter at active zones

Table of Contents: “…Contents: Vesicular release of transmitter -- Structural heterogeneity of active zones -- Filamentous structures at active zones -- Mechanisms & measurement of vesicular release -- Fluctuation analysis -- Short-term plasticity models -- Recovery from synaptic depression -- Presynaptic capacitance measurements -- Capacitance measurements (Lock-in amplifier & passant terminals) -- Calcium microdomains -- Calcium sensitivity of vesicle fusion -- Nomenclature of synaptic vesicle pools -- Two pools of release-ready vesicles -- Vesicle recruitment during synaptic activity -- Calcium dependence of vesicle recruitment -- Activity dependent speeding of recruitment.…”
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Macrophage in asthma

Table of Contents: “…Contents: Contributing factors to asthma include abnormal epithelium, predominant Th2 cytokines, and inappropriate repair leading to airway remodeling -- Alternative activation of macrophages (via IL-4 and IL-13) leads to chitinase production -- Interstitial macrophages may have regulatory role (via IL-10) -- IL-13 may be a key cytokine in activation of airway macrophages -- IL-13 amplifies features of asthma such as airway hyperresponsiveness and mucus production.…”
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Series (Advances in asthma)
Series (Macrophage heterogeneity and function)

Molecular identification of the CRAC channel

Table of Contents: “…Contents: Background on Calcium signaling and ion channels in the immune system, role of CRAC channels in lymphocyte activation -- Discovery of Stim and STIM1 by RNA interference screen in Drosophila S2 cells -- Stim as an ER Calcium sensor and as a messenger to the plasma membrane -- Genome-wide RNA interference screen and the discovery of Orai -- Amplifying CRAC current by co-expression of Stim and Orai -- Molecular identification of CRAC channels by altered ion selectivity in a mutant of Orai -- How does the CRAC channel activate?…”
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