Search Results - "Genetics"

Evolutionary genetics the detection of natural selection using molecular data /

Table of Contents: “…Contents: Mutation and variation in populations -- The fate of mutations under random genetic drift and natural selection -- Measures of variation -- Detecting signatures of natural selection in genomic data.…”
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Drosophila genetics the first 25 years /

Subjects: “…Drosophila genetics. 113048…”
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The genetics of pain

Table of Contents: “…Contents: Variability in pain sensitivity and analgesia -- Heritability of pain -- Genetic and environmental contributions to pain -- Pain genes -- Monogenic pain disorders -- Association studies -- Inbred mouse strains and strain differences -- Genetic correlations among pain phenotypes -- Quantitative trait loci (QTLs) -- Melanocortin-1 receptors and pain -- Formalin test QTLs -- Haplotype mapping -- Atp1b3 and formalin pain.…”
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Genetic toxicology

Table of Contents: “…Contents: Mutagenicity testing -- Clastogenicity testing -- Additional assays -- Regulatory genetic toxicology -- Current regulations -- In vitro mutagenicity and clastogenicity -- In silico -- Integration of results and data interpretation -- Genotoxic impurity testing.…”
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Genetics in forensics

Subjects: “…Forensic genetics. 114054…”
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Population genetics

Table of Contents: “…Contents: Studying human evolution using population genetics -- The history of population genetics -- Demographic models -- DNA datasets -- Example genealogies -- Calculating summary statistics (number of polymorphisms; average pairwise difference; Tajima's D) -- Inference -- Statistical significance -- Current work in population genetics -- Population genetics studies in Africa.…”
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Genetics of COPD

Table of Contents: “…Contents: COPD-important world-wide cause of morbidity and mortality -- Clear evidence of a genetic contribution to disease risk -- Genome wide association studies have identified genes predicting lung function -- Role of these genes in COPD pathophysiology.…”
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Genetics of epilepsy

Table of Contents: “…Contents: Epilepsy and genetics -- Significant contribution of genetics to many epilepsies -- Many types of variation, and methods to detect them -- Importance of correct interpretation -- Will likely revolutionise understanding.…”
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The genetics of glioblastoma

Table of Contents: “…Contents: Classifications of glioblastoma -- Isocitrate dehydrogenase 1 mutation as the fundamental mutation in malignant glioma -- The genetic mechanism of telomere maintenance in gliomas -- Molecular subclassifcation of gliomas.…”
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Genetic testing prediction vs. risk /

Table of Contents: “…Contents: Genetic principles -- "Traditional" Sanger sequencing and how it led to development of high throughput sequencing -- The principle underlying high throughput sequencing -- Some applications of high throughput sequencing including obesity -- The difference between risk vs. prediction in genetics.…”
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The genetics of stuttering

Table of Contents: “…Contents: The genetics of stuttering -- Genetics -- Neuroscience -- Speech and language pathology -- Twin and adoption studies -- Medical genetics -- Mice as a model for stuttering.…”
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Genetic counseling preconception, prenatal, perinatal /

Table of Contents: “…Contents: Genetic counseling -- Prenatal genetic diagnosis -- Congenital malformations -- Ethics -- Confidentiality -- Law.…”
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An introduction to statistics for statistical genetics part 2, models and techniques common in statistical genetics /

Table of Contents: “…Contents: Hidden Markov models -- Imputation and genetic imputation -- Principal Component Analysis (PCA) -- Mixed Models -- Shrinkage and regularisation methods.…”
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Population genetics considerations

Table of Contents: “…Contents: Population genetics: definitions and terminology -- Genetic association -- Association between disease and a gene -- Linkage equilibrium/disequilibrium -- Hardy-Weinburg equilibrium/disequilibrium -- Population inbreeding -- Population substructure -- Bias and variance inflation in genetic association tests -- Genomic control.…”
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Genetic determinants of agranulocytosis

Table of Contents: “…Contents: Agranulocytosis -- Adverse drug reactions -- Etiological mechanisms -- Idiosyncratic drug reactions -- Genetic and immunologic background -- Antipsychotic induced agranulocytosis -- Clozapine -- Olanzapine -- Future strategies of research.…”
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Genetic determinants of metabolism clinical applications in psychiatry /

Table of Contents: “…Contents: Factors that determine psychiatric importance of genetic variants -- Consequences which arise from genotyping -- Drugs are metabolized via the polymorphic cytochrome P450 enzyme CYP2D6 -- Differences in pharmacokinetic parameters for tricyclics, some SSRIs, other antidepressants, typical and some atypical antipsychotic drugs -- Effects on therapeutic efficacy and adverse events -- Indication for genotyping in psychotropic drug treatment -- Future research to close the gap between pharmacogenetic research and clinical practice.…”
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Genetic association studies the candidate gene approach /

Table of Contents: “…Contents: Background of genetic studies -- Structure of a gene -- Simple association -- Linkage disequilibrium and haplotypes -- Multi-marker association -- Family-based association -- Practicalities of programs and power.…”
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Genetic defects and calcium

Table of Contents: “…Contents: General concepts of calcium signaling -- Mechanisms of calcium extrusion/uptake -- Mechanisms of calcium release from the ER/SR -- General concepts about plasma membrane calcium channels -- Genetic defects of calcium release channels -- Genetic defects of plasma membrane calcium channels -- Genetic defects of calcium pumps -- Novel findings on genetic defects of store dependent calcium channels.…”
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Series (Calcium signaling I)
Series (Calcium signaling II)

Chloroplast genetic engineering

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Human population genetics lifespan /

Table of Contents: “…Contents: Human lifespan as a heritable trait -- Lifespan phenotypes -- Genetic epidemiology of human lifespan -- The genetic architecture of human longevity -- Genetic study designs in longevity research.…”
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