Search Results - "Cancer"

Viruses and cancer

Table of Contents: “…Contents: Oncogenic viruses of animals and humans have given us insights into cancer in general -- Specific genes involved in cancer such as oncogenes and tumor suppressor genes were first discovered through research on tumor viruses -- Only a subset of viruses cause cancer -- For cancers caused by viruses, the viruses are a necessary but insufficient cause of the disease -- Cancer is multifactorial and different risk factors act together -- Vaccines hold great promise to reduce the cancer burden -- The incidence is higher in immunodeficient people -- Transplant recipients and AIDS.…”
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Targeting cancer designing drugs against Hsp90 /

Table of Contents: “…Contents: Heat shock protein 90 (Hsp90), a target in cancer -- Discovery of the first known Hsp90 inhibitor, geldanamycin -- Use of geldanamycin to understand the role of Hsp90 in malignant transformation -- Discovery of novel Hsp90 inhibitors -- Development and applications of Hsp90 inhibitors.…”
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Pancreatic cancer

Table of Contents: “…Contents: General epidemiologic data for pancreatic cancer -- Review risk factors for pancreatic cancer -- Clinical presentation and diagnostic modalities for pancreatic cancer -- Current status for early detection, diagnosis and staging of pancreatic cancer -- Treatment of pancreatic cancer.…”
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Cancer vaccines part 1 of 2 /

Table of Contents: “…Contents: The hallmarks of cancer -- Categories of cancer-associated antigens -- Viral & non-viral cancers: vaccine targets -- Immunotherapeutics -- Immunologic reagents approved for cancer therapy -- Clinical outcome based on immune response -- CTL-based therapy -- Virus-specific CTL adoptive transfer therapy -- Immunotherapy for Melanoma.…”
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Series (Immunotherapy of cancer)
Series (Vaccines)

Cancer vaccines part 2 of 2 /

Table of Contents: “…Contents: HPV infection & prevention strategies -- Global cervical cancer prevalence -- HPV induced lesions & cancers -- Cell-mediated immune response to HPV -- Synthetic Long Peptide (SLP) vaccine concept -- Vulval intraepithelial neoplasia (VIN) vaccine -- Combining chemotherapy & SLP vaccination.…”
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Series (Immunotherapy of cancer)
Series (Vaccines)

Pancreatic cancer

Table of Contents: “…Contents: General epidemiologic data for pancreatic cancer -- Review risk factors for pancreatic cancer -- Clinical presentation and diagnostic modalities for pancreatic cancer -- Pancreatic cystic lesions -- Current status for early detection, diagnosis and staging of pancreatic cancer -- Treatment of pancreatic cancer -- Current needs: challenges and opportunities.…”
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Ovarian cancer part 1 of 2, molecular characterization /

Table of Contents: “…Contents: Introduction to ovarian cancer -- Past therapies for ovarian cancer and their failure -- Heterogeneity in ovarian tumors -- Identification of types of ovarian cancer cells -- Molecular characterization of ovarian cancer cells -- Hierarchy within the ovarian tumors.…”
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The biology of cancer

Table of Contents: “…Contents: Present general hallmarks of cancer -- Explain how cancer is initiated through activation of oncogenes and deactivation of tumour suppressors -- Highlight what makes these oncogenes and tumour suppressors so special -- Show different ways in which these proteins can modify cell signalling to lead to cancer -- Introduce the notion that cancer is not only about the cancer cell but also about the environment -- Give examples of how we can exploit this combined knowledge to develop cancer therapeutics and the associated challenges.…”
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Ovarian cancer progression of tumors /

Table of Contents: “…Contents: The origin of ovarian cancer -- Epithelial ovarian cancer cells -- The formation of ovarian tumors -- Luteal cells and ovarian cancer -- The metastatic process in ovarian cancer -- Response to chemotherapy -- The recurrence of cancer stem cells.…”
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Cancer immunology

Table of Contents: “…Contents: Function and regulation of cell division -- The hallmarks of cancer -- Immune surveillance -- Evidence of anti-tumour T-cell responses -- T cell recognition of cancer cells -- Evasion of tumour immunity -- Immune escape -- Immune suppression.…”
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Series (Immune system)
Series (Molecular basis of cancer)

Cancer immunotherapy

Subjects: “…Cancer Immunotherapy. 84884…”
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Series (Immune system)
Series (Molecular basis of cancer)

Cancer pathology

Table of Contents: “…Contents: Cancer pathology -- Histology -- Melanoma -- GI colon cancer -- Breast cancer.…”
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Cancer pain

Table of Contents: “…Contents: Trends in cancer pain -- Etiology of cancer pain -- Cancer survivors -- Problems faced by cancer survivors who have persistent pain -- Tumor and treatment related pain -- Chronic pain syndromes associated with cancer treatment -- Guidelines for treating cancer survivors who experience persistent pain -- Challenges in managing pain associated with malignancies.…”
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Colorectal cancer and hereditary colon cancer syndromes

Table of Contents: “…Contents: Colorectal cancer is a molecularly heterogeneous disease known to arise from two distinct origins, the adenomatous and serrated pathways -- Sessile serrated polyps, also known as sessile serrated adenomas, and traditional serrated adenomas are believed to be the precursor lesions for serrated carcinomas which account for up to 30% of sporadic colorectal cancers -- When colorectal polyps or cancer occur in multiple generations, numerous relatives, at a young age of onset or in association with unusual numbers of lesions or extra-colonic tumors, a hereditary colorectal cancer syndrome should be suspected as a potential cause -- The ability to recognize a patient with a hereditary colorectal cancer syndrome allows a practitioner to stratify her or his patient's lifetime cancer risk and devise prevention and management strategies for risk reduction in the patient and family once the diagnosis is confirmed.…”
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Targeting the cancer microenvironment inflammatory breast cancer management /

Table of Contents: “…Contents: Introduction to inflammatory breast cancer -- Epidemiology of IBC -- Approaches to treatment of IBC -- Molecular analysis of IBC -- The contribution of microenvironmental factors to the aggressiveness of IBC -- Targeting the cancer microenvironmental factors for treating IBC -- The involvement of macrophages and mast cells in the aggressiveness of IBC.…”
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RNA interference and cancer a revolution? /

Table of Contents: “…Contents: Cancer overview -- RNA interference to understand cancer -- Natural short RNAs in cancer -- RNA interference to fight cancer.…”
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Cancer pain control an evidence-based approach /

Table of Contents: “…Contents: Importance of cancer pain control -- Assessment and sources of cancer pain -- Selecting agents according to pain mechanism -- The WHO ladder -- Nonopioids and adjuvants -- Opioids -- Side effects -- Neuraxial drug delivery -- Nondrug modalities -- What does the published evidence show?.…”
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Principles of cancer treatment surgery, radiotherapy, chemotherapy, immunotherapy /

Table of Contents: “…Contents: Historic principles leading to modern cancer treatments -- Specific reviews of surgery, radiotherapy, chemotherapy, hormone therapy and immunotherapy development -- Significant developments in present use -- Modern concepts using combined modality approaches -- Latest technological developments in radiotherapy -- Latest developments and implementation of immunotherapy -- Discussion of near future events and possibilities.…”
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Understanding cancer trends

Table of Contents: “…Contents: Current trends in cancer incidence, mortality and relative survival in the US -- Understanding how improvements in prevention, early detection and treatment affect these trends -- How demographic changes affect the number of cancer cases and deaths but not the age-standardized incidence or death rates -- Specific cancer sites for which the incidence and/or death rates are changing -- Role of prevention, early detection, and improvements in treatment in reducing the burden of cancer.…”
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Therapy in cancer 2008 quo vadis? /

Table of Contents: “…Contents: Why pursuing new therapeutic approaches in cancer is important -- Prevention and screening -- Current cancer therapy: non-surgical -- Most chemotherapy targets DNA -- Chemotherapy effects -- Current state of cancer therapy: efficacy and toxicity -- Molecular pathogenesis of cancer -- Pursuing targeted therapy in cancers -- Targeted biologic therapies -- Evolving targets and agents -- Shift from chemotherapy to targeted agents -- Clinically established molecular targets in malignancies -- Targeted therapy: proteins and small molecules -- Changes brought about by targeting: efficacy and toxicity -- Biomarkers in drug development -- What is currently known: angiogenesis -- The VEGF family and its receptors -- Bevacizumab and Sorafenib -- Does toxicity correlate with response? …”
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