Search Results - "Environmentalism."

Environmental scleroderma the evidence for putative triggers /

Table of Contents: “…Contents: Occupational or environmental exposures with the subsequent development of systemic sclerosis (SSc, scleroderma) -- Exposure to organic solvents and silica dust as a risk factor for SSc -- Occurrence of scleroderma-like conditions in an epidemic fashion following known exposures -- Demonstration of exposure to ingested or intravenous substances resulting in severe and long lasting dermal fibrosis.…”
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Occupational and environmental influences on the development and course of lupus

Table of Contents: “…Contents: Role of genetic susceptibility in the etiology of systemic lupus erythematosus (SLE) -- Demographic risk factors for SLE -- Epidemiologic and experimental research on occupational exposures (respirable silica dust and solvents) and risk of developing SLE -- "Lifestyle" factors (smoking, use of hair dyes) and risk of developing SLE -- Ultraviolet radiation and risk of developing SLE -- Research on exposures and SLE severity (disease activity and damage) -- Examples of specific gene-environment interactions -- Environmental pollutants and SLE.…”
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Infectious environmental factors and systemic lupus erythematosus

Subjects: “…Environmental Exposure. 110068…”
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Biomarkers of exposure

Subjects: “…Environmental Exposure. 110080…”
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Genetic susceptibility in granulomatous disorders chronic beryllium disease and sarcoidosis /

Table of Contents: “…Contents: Role of genetics x exposure in environmental lung disease -- Granulomatous disorders and immunologic mechanistic basis: berylliosis and sarcoidosis -- Immunogenetics that may apply generally to granulomatous disorders -- Berylliosis: genetic epidemiology studies, functional genomics and gene x environment interaction studies -- Role of exposure vs. genetic basis -- Sarcoidosis: genetic epidemiology studies, attempts at functional genomics and directions for research to use clinical phenotype and genotype information to improve and help direct the search for an unknown causative agent -- Possible implications for other (non-granulomatous) environmental lung disorders.…”
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Gene-by-environment interactions in Chronic Obstructive Pulmonary Disease

Subjects: “…Environmental Exposure. 110142…”
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Gene by environment interaction in asthma

Table of Contents: “…Contents: Interaction definition -- Types of environmental exposures -- G x E interaction: key issues and study designs -- Potential methodologic issues -- G x E interaction in linkage studies of asthma -- ADRB2, GSTM1 and CD14 and smoking -- TLR4 and endotoxin -- Asthma pharmacogenetics -- Advantages and disadvantages to studying G x E interactions.…”
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Molecular epidemiology of lung cancer

Table of Contents: “…Contents: The influence of host factors on individual susceptibility to tobacco smoke -- The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens -- Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential -- Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors -- Polymorphisms in genes and the association of this with lung cancer development -- The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet.…”
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GIS and spatial statistics

Table of Contents: “…Contents: Introduction to GIS and its role in environmental epidemiology -- Ways that GIS can be used to quantify environmental exposures -- Statistical methods for analyzing spatial data -- Examples where GIS has played a useful role.…”
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Gene-by-environment interaction: study designs and analytical methods

Subjects: “…Environmental Exposure. 110347…”
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Racial and ethnic variation in systemic lupus erythematosus and systemic sclerosis (Scleroderma)

Table of Contents: “…Contents: Epidemiology of lupus and scleroderma -- Racial and ethnic variation in disease susceptibility and expression -- Geographic variation -- Environmental triggers -- Hypothetical disease mechanisms of environmental triggers -- Future research directions.…”
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Analysis of SNP haplotypes

Subjects: “…Environmental Exposure. 110321…”
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Statistical issues in epidemiologic studies of gene-environment interaction

Table of Contents: “…Contents: Gene-environment interaction in the development of human traits, including disease -- Conceptual and analytical challenges -- Joint analysis of data on both genetic and environmental factors from epidemiologic studies as a way to increase power to detect a polymorphism (or an exposure) that is associated with disease risk -- Study designs -- Statistical modeling issues in the analysis of data -- Sample size and power calculations for a range of designs -- Specification of parameters -- Ordinal coding -- Hierarchical models -- The analysis of highdimensional "pathway" data (multiple related genes and environmental exposures).…”
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Indians, twins and scleroderma genetic and genomic studies /

Subjects: “…Environmental Exposure. 110254…”
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Ethical issues in molecular epidemiology and studies of gene-environment interactions

Table of Contents: “…Contents: An experiment in science policy: the ethical, legal and social implications (ELSI) program -- Environmental response genes -- Applying genetic techniques in risk assessment: toxicogenomics -- Ethical issues in the application of genomic technologies in public health -- Misconceptions about genetic information -- Potential misapplications of genomic information or technologies -- Discrimination on the basis of genetic information -- Problems in assigning responsibility for poor health based upon genetic information -- The scope of future research with biological materials: ethical considerations.…”
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Drug induced lupus and lupus-like syndromes

Subjects: “…Environmental Exposure. 109807…”
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The immunology of multiple sclerosis

Table of Contents: “…Contents: Multiple sclerosis (MS) -- Form of the disease -- Environmental exposure and genetic susceptibility -- Defective immune regulation -- How is MS treated? …”
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Epigenetics and inheritance

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Life course of the brain during normal aging and Alzheimer's disease

Table of Contents: “…Contents: Neuropathology of Alzheimer's disease (AD) -- Normal changes of the aging brain -- Genetic influences on AD and normal brain aging -- Environmental exposures and the risk of AD -- AD drugs and drug trials.…”
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