Search Results - Drugs
Suggested Topics within your search.
Suggested Topics within your search.
- drug therapy 303
- therapeutic use 148
- Chemotherapy 143
- methods 138
- Treatment 118
- prevention & control 103
- Drug development 94
- drug effects 91
- Drug Discovery 90
- therapy 84
- pharmacology 83
- metabolism 80
- Neoplasms 76
- Drugs 71
- immunology 67
- Cancer 64
- Pharmaceutical Preparations 64
- Research 60
- genetics 60
- Development 59
- Antineoplastic Agents 56
- Vaccines 51
- Diseases 50
- Prevention 46
- Antineoplastic agents 44
- Drug Design 43
- Pharmacogenetics 43
- Vaccination 43
- epidemiology 42
- pathology 42
-
1
-
2
Of genes and drugs genetic determinants of adverse drug reactions /
Published 2007Table of Contents: “…Contents: Type A and B Adverse Drug Reactions (ADRs) -- Pharmacokineticpharmacodynamic paradigm -- ADME framework -- Mechanisms of ADRs -- Pharmacogenetics and pharmacogenomics -- Polygenic traits -- Environmental factors -- Phenotype and endophenotype -- Candidate genes -- Association and linkage disequilibrium.…”
Get full text
Series
Electronic Video -
3
Psychotropic drugs
Published 2007Table of Contents: “…Contents: Discovering psychotropic drugs -- Psychotropic drugs: basic mechanisms of action.…”
Get full text
Series
Electronic Video -
4
Drug development from discovery to manufacture /
Published 2022Table of Contents: “…Contents: Drug safety -- Drug efficacy -- Research and development -- Drug discovery -- Preclinical research -- Clinical trials.…”
Get full text
Electronic Video -
5
New drugs for asthma
Published 2021Subjects: Get full text
Series (Periodic reports)
Series (Advances in asthma)
Electronic Video -
6
New drugs for asthma
Published 2011Table of Contents: “…Contents: Improvements in existing therapies have been the main approach -- New classes of drug in development -- Upcoming oral and inhaled therapies that target inflammation in asthma -- Patients with severe disease -- Inflammation in severe asthma is usually corticosteroid insensitive.…”
Get full text
Series
Electronic Video -
7
Current drugs for TB treatment
Published 2013Table of Contents: “…Contents: Historical perspective -- Timeframe for drug and regimen development -- Current regimens -- Current WHO and ATS guidelines -- Treatment principles -- Pathological basis of action of TB drugs -- Drug profiles -- Limitations of current treatment regimens & special situations -- Problems with first line therapy -- Brief consideration of drug resistance.…”
Get full text
Series
Electronic Video -
8
Antiviral drugs (non-HIV)
Published 2018Table of Contents: “…Contents: Why do we need antiviral drugs? -- Overview of approved antiviral drugs -- Antiviral targets mechanisms and resistance -- Hepatitis C virus: biology and current drugs -- Hepatitis B virus: biology and treatments -- Herpesvirus drugs -- Influenza virus: approved drugs -- Broad-spectrum antivirals -- Diseases for which we need antivirals.…”
Get full text
Series
Electronic Video -
9
Narkomania : Drugs, HIV, and Citizenship in Ukraine /
Published 2019Table of Contents: “…Homegrown -- What counts when you're counting -- A deficit of desire -- Star wars and the state -- Drugs of revolution -- Sovereignty and abandonment.…”
Full text available:
Electronic eBook -
10
Where did drugs come from?
Published 2013Table of Contents: “…Contents: Drug discovery strategies -- How drugs were discovered -- The paradox between empirical and hypothesis driven drug discovery -- How drugs work/molecular mechanism of action is at the core of the paradox -- Practical application of new knowledge.…”
Get full text
Series
Electronic Video -
11
Anti-seizure drugs discovery and development /
Published 2013Table of Contents: “…Contents: Seizures and epilepsy -- Drugs for the symptomatic treatment of seizures -- Finding new Anti-Seizure Drugs is a combination of serendipity, screening and rational approaches -- Drug Development -- Preclinical studies -- Controlled Clinical Trials are needed to prove that an anti-seizure drug is effective.…”
Get full text
Series (Epilepsy and seizures)
Series (Drug discovery)
Electronic Video -
12
CNS drug design
Published 2008Table of Contents: “…Contents: Central nervous system diseases -- Drug market for CNS disorders -- Traditional CNS drug targets -- Novel CNS drug targets -- Multiple obstacles for drug delivery to CNS -- Pathways for drug exchange within the CNS -- The structure of brain capillaries impedes uptake -- Measures of drug uptake and distribution in brain -- BBB permeability and solute lipid solubility -- Tissues capillary PS and 95 per cent equilibration time -- Cerebral blood flow affects drug uptake and Kin -- Initial uptake vs. steady-state distribution -- Plasma protein binding and brain drug uptake -- Brain capillary drug transporters -- Transporters and drug distribution across BBB -- "Enzymatic" blood-brain barrier -- Relation between bound and free drug -- Free drug distribution ratio at steady state -- BBB changes in pathology and disease -- Drug-like properties to cross the BBB -- Early findings in BBB drug uptake -- Measures of lipophilicity -- Passive permeability across lipid membranes -- Drug ionization -- Influence of pH on neutral fraction -- Lipinski "rule of five" -- Impact of hydrogen bonds and alkyl groups -- Positive CNS drugs -- Poor CNS drug -- in vitro measures -- In vivo measures -- Methods to improve brain uptake -- Simple rules for efflux transporters -- % drug distribution to brain -- Biologic compounds -- Brain pharmacokinetics.…”
Get full text
Series (Blood-brain barrier)
Series (Small molecule drug discovery)
Electronic Video -
13
Spinal drug delivery technology, biology and toxicology /
Published 2009Table of Contents: “…Contents: Pain: concepts and early anatomy -- Role of sensory nerves and spinal cord -- Enabling technology for spinal anesthesia -- Rapid evolution of spinal anesthetic delivery in the US -- Early appreciation of risks of spinal anesthesia -- Modulation of spinal processing -- Targeting drugs at spinal function -- Other systems which regulate spinal afferent transmission -- Pain selectively diminished by spinal opioids -- Spinal mu/delta opioid action -- Spinal analgesics: animal and human pain -- Safety of spinal drugs -- Early safety issues with spinal anesthetic -- Classes of spinal toxicity -- Intrathecal lidocaine and toxicity -- Spinal toxicity: root, parenchyma, meningeal -- Human intrathecal morphine: granuloma -- IT morphine and granulomas concentration vs. dose -- Future and neuraxial drug delivery.…”
Get full text
Series
Electronic Video -
14
Drug resistant tuberculosis biology, epidemiology and control /
Published 2009Table of Contents: “…Contents: Natural history and epidemiology of TB -- Discovery of antibiotics -- Drug combinations as used in TB control programmes worldwide -- How drug resistance arises -- Geographical distribution of drug-resistant TB -- TB drug resistance and HIV/AIDS -- Reversing the spread of drug-resistant TB.…”
Get full text
Series
Electronic Video -
15
Antiretroviral drug resistance
Published 2011Table of Contents: “…Contents: HIV replication and biological basis of drug resistance -- Antiviral drugs -- Emergence of drug resistance in practice -- Measurement of drug resistance.…”
Get full text
Series
Electronic Video -
16
Prodrugs and drug delivery
Published 2013Table of Contents: “…Contents: Prodrugs and drug delivery -- Prodrug concept and designing prodrugs -- Solving ADMET properties -- Prevalence, recent approvals and best-sellers.…”
Get full text
Series
Electronic Video -
17
Enzymology in drug discovery part 1 of 2 /
Published 2013Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
Get full text
Series
Electronic Video -
18
Enzymology in drug discovery part 2 of 2 /
Published 2013Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
Get full text
Series
Electronic Video -
19
Biomarkers in drug development potential use and challenges /
Published 2013Table of Contents: “…Contents: Biomarkers in drug development -- Classes of biomarkers -- Crisis in pharmaceutical development -- Potential value of biomarkers and personalized medicine to enhance probability of success -- Challenges (biology, pre-analytical, analytical) -- Possible mitigation.…”
Get full text
Series (Biomarkers)
Series (Small molecule drug discovery)
Electronic Video -
20
Pulmonary drug delivery
Published 2017Table of Contents: “…Contents: Pulmonary drug delivery -- Therapeutic targets -- Drug categories -- Lung deposition and clearance -- Inhaled drug products -- Mechanism of droplet formation pMDIs -- In vitro tests -- In vivo considerations.…”
Get full text
Series (Drug delivery)
Series (Advances in asthma)
Electronic Video