Search Results - "glucose"

Glucose-6-Phosphate dehydrogenase deficiency

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Glucose transport across the blood-brain barrier

Table of Contents: “…Contents: Functions of the neurovascular unit -- Brain energy substrates -- Pathways across the blood-brain barrier -- Glucose utilization and transport -- Glucose uniporters -- Kinetic transport parameters -- Glucose transport in baseline and during activation -- Neurovascular coupling -- Neurometabolic coupling -- Neurobarrier coupling -- Dynamic changes of glucose concentration -- GLUT-1 stimulation in vitro and in vivo -- Roadmaps for glucose from blood to neurons.…”
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The blood-brain barrier in Alzheimer's disease

Table of Contents: “…Contents: The blood-brain barrier -- Alzheimer's disease -- The blood-brain barrier in Alzheimer's disease -- Cerebral blood flow -- Glucose transport -- Aβ clearance -- Blood-brain barrier leakage -- Blood-brain barrier repair.…”
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Transporters in drug delivery

Table of Contents: “…Contents: Biotransporters in drug delivery -- Classification of transporters -- P-glycoprotein transporters -- Transporters for cancer therapy -- Solute carrier transporters -- Facilitative glucose transporters -- The substrates and inhibitors of different transporters -- Effect of transporters in drug delivery -- Pharmacological applications.…”
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Mathematical modeling in immunology

Table of Contents: “…Contents: The role of modelling in immunology -- A first simple model: viral clearance -- The equation of the simple model -- Apheresis experiment -- Models of T-cell dynamics: proliferation -- Telomeres -- Expression of Ki67 -- Deuterated glucose -- T cell Receptor Excision Circles (TREC) dynamics -- Models explain contradictory observations -- Models of T-cell dynamics: thymic production -- Models help design experiments.…”
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Series (Immune system)

O-GlcNAc, an essential regulator of numerous cellular pathways

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Roles of AMPK in energy homeostasis and nutrient sensing

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Diagnosis and screening of diabetes

Table of Contents: “…Contents: Define glucose levels for diabetes diagnosis -- Retinopathy and glycaemia -- Limitations of glucose measurement -- Limitations of HbA1c measurement -- Screening for diabetes with questionnaires.…”
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The eye and diabetes

Table of Contents: “…Contents: Complications from diabetes -- Diabetic retinopathy -- Classification of diabetic retinopathy -- Classification of diabetic macular edema -- Clinical assessment of diabetic retinopathy -- Optical coherence tomography -- Epidemiology of diabetic retinopathy -- Strategies of diabetic retinopathy management -- Glucose control remains critical -- Blood pressure just as important as glucose -- Role of lipids -- Multi-factoral interventions -- Ocular treatment strategies of diabetic retinopathy -- Novel therapy: Intraocular steroids -- Anti-VEGF agents -- Screening and awareness.…”
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Evolution of the diagnostic criteria for diabetes

Table of Contents: “…Contents: Description & symptoms of diabetes -- Criteria for screening and challenges -- Abbreviated history of diabetes diagnosis -- Glucose distribution (unimodal & bimodal) -- Cutoff values & mathematical manipulations -- Different criteria for diagnosis of diabetes & diabetes classifications -- WHO criteria for diabetes mellitus -- Relationship between FPG & 2hr value on OGTT -- Decisions of the expert committee -- Glycation -- The Pima Indians, Egyptian, and NHANES III studies -- Prevalence of retinopathy -- Oral glucose tolerance tests -- Quantitation of variation -- Using HbA1c levels to diagnose diabetes -- Expert committee on diagnosis of diabetes -- Screening for diabetes before and after 2010 ADA criteria and recommendations for diabetes diagnosis.…”
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Physical activity, sedentary behaviour and diabetes

Table of Contents: “…Contents: Epidemiological thinking: physical activity & health -- Skeletal muscle, glucose disposal and muscle glucose uptake -- Recent advances in exercise and T2DM -- Exercise modality, combination training and rationale for strength, resistance training -- Exercise guidelines for T2DM (2006) -- Change in HbA1c -- "Stickiness" -- Community centre vs. home based resistance training -- Physical activity recommendations and public health -- The "sitting orientated" society -- Sedentary behaviours and mortality -- Movement and posture measurement devices -- Sedentary time and breaks (NHANES) -- Australian adults' overall daily behaviour patterns -- Rethinking the physical activity paradigm -- Pathophysiology of prolonged sitting -- Sedentary time and light-intensity activity -- How to reduce sitting time and guidance for prescribing exercise and physical activity promotion -- ACSM position stand.…”
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Managing hyperglycaemia in people with DM and CKD part 2, cardiovascular disease (CVD) involvement /

Table of Contents: “…Contents: The need to individualise glycaemic control in DKD -- The role of new agents in reducing development and progression of DKD -- The need for co-ordinated DM care in haemodialysis -- Logical and inappropriate combination blood glucose lowering therapies in DKD -- Safe management of DKD during acute illness.…”
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Glycan regulation of receptor functions

Table of Contents: “…Contents: Review of cell surface glycoprotein receptors -- Glucose transporters 2 -- Integrins -- Epidermal growth factor receptor -- Platelet Endothelial adhesion molecules -- Transforming growth factor beta receptor -- the common structure of these receptors -- Production of N-glycans -- N-glycans in disease: diabetes and COPD.…”
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Cardiovascular prevention in type 2 diabetes

Table of Contents: “…Contents: Diabetes mellitus as an equivalent of cardiovascular disease and secular trends of cardiovascular outcomes -- Multi-factorial therapy as the golden treatment paradigm for cardiovascular prevention -- Statins in primary and secondary intervention -- Blood pressure lowering therapy under inclusion inhibition of the rennin-angiotensin-aldosterone system -- Outcome evidence of blood glucose lowering therapy.…”
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General management

Table of Contents: “…-- Early mobilization -- Monitoring of neurological status and vital physiological functions -- Blood pressure management -- Cardiac care -- Oxygen saturation -- Blood glucose management -- Body temperature -- Medical complications -- Pain -- Swallowing problems -- Nutrition -- Fall and fractures -- Deep venous thrombosis -- Urinary tract problems -- Seizures.…”
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Molecular brain imaging (PET) in diseases with dementia

Table of Contents: “…Contents: Brain imaging with positron emission tomography (PET) for dementia diagnosis and research -- Cerebral glucose metabolism in mild cognitive impairment, Alzheimer's disease, dementia with Lewy bodies, frontotemporal dementia & depression -- Imaging of pathological markers (beta-amyloid and tau) in Alzheimer's disease -- Imaging of neurotransmitters and receptors, in the dopaminergic and cholinergic system -- Multiple systems profiling in dementia, Parkinson's and related motor disorders.…”
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Series (Periodic reports)
Series (Neurodegenerative diseases)

Glycoprotein maturation and quality control in the endoplasmic reticulum

Table of Contents: “…Contents: Protein maturation in the secretory pathway -- ER glycoforms -- The glyco-code of the ER -- Calnexin and calreticulin -- Cotranslational folding -- Influenza hemagglutinin -- Oxidation of HA -- HA truncations -- Type I membrane proteins -- Disease states involving ER folding and quality control -- Structural determinants that cause retention -- ER retention signals -- Calnexin binding cycle -- GT or UDP glucose glycoprotein: glycosyltransferase -- Degradation of misfolded proteins -- Carbohydrate trimming -- EDEM1 functions.…”
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Modifications of pyruvate handling in health and disease

Table of Contents: “…Contents: Potential metabolic fates of pyruvate -- Lactate transport -- Role of pyruvate dehydrogenase complex (PDC) -- Regulation of PDC -- Mechanisms of activation of PDC by pyruvate dehydrogenase phosphatases -- Pyruvate dehydrogenase kinase (PDK) expression and regulation -- Multi-site phosphorylation -- Transcription factors regulating PDK4 expression -- Anaplerosis and cataplerosis -- Pyruvate carboxylase -- Insulin secretion and action -- Glucose/fatty-acid cycle -- Consequences of PDK4 upregulation -- Disorders of pyruvate handling.…”
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Genetic conflicts in human pregnancy

Table of Contents: “…Contents: The association of maternal provisioning of a fetus and opportunity cost -- The relationship between maternal investment in fetus to the benefit to the fetus and the cost to its siblings -- The maternal-fetus unit: genes and their direct benefit to the fetus and indirect cost to its siblings -- Syndromes associated with the imprinted cluster of genes of human chromosome 11p15.5: Beckwith- Wiedemann syndrome and Silver-Russell syndrome -- 3 potential areas for conflict during pregnancy: whether to carry/miscarry the embryo, nutrient quality of maternal blood and the volume of blood reaching the placenta -- Placental hormones and fetal attempts to manipulate maternal physiology for fetal benefit -- Maternal carbohydrate metabolism: glucose and insulin levels in the maternal blood, and maternal insulin sensitivity -- The maternal-fetus blood circulation during pregnancy and the systemic blood supply shared between them.…”
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The treatment of type 1 diabetes in children and youth

Table of Contents: “…Contents: The SEARCH study -- The latency period in the development of T1D -- Time to diabetes by number of Abs -- TrialNet and Immune Tolerance Network international consortia -- Prevention and early diagnosis -- The diagnosis of T1D in children and youth -- Work up of diabetes type in youth -- Catastrophe at diagnosis: DKA -- What is the course of type 1 diabetes -- DCCT, EDIC and rate of severe hypoglycemia -- The importance of glycemic control -- The insulin pump: more like a healthy pancreas -- CSII reduces incidents of severe hypoglycemia -- Continuous glucose monitoring -- Early control and beta-cell preservation -- STAR 3 study -- A1C reduction is correlated with sensor use -- Prevalence of CVD risk factors in youth -- The role of healthcare provider in treatment -- Evolution of a fully-automated delivery system -- How does LGS work? …”
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