Search Results - "chromatin"
Suggested Topics within your search.
Suggested Topics within your search.
- Gene Expression Regulation 32
- Transcription, Genetic 30
- Chromatin 25
- genetics 25
- metabolism 22
- Epigenesis, Genetic 20
- Eukaryotic Cells 19
- physiology 16
- Genetic regulation 15
- Transcription Factors 15
- Epigenesis 14
- Genetic transcription 14
- DNA 9
- DNA Methylation 8
- Proteins 8
- Histones 7
- Gene Expression Regulation, Developmental 6
- Gene Silencing 6
- Gene expression 6
- Neoplasms 6
- Cell Cycle 5
- Chromatin Assembly and Disassembly 5
- Gene Expression 5
- Gene silencing 5
- Genetic aspects 5
- Genetics 5
- Polycomb-Group Proteins 5
- Cancer 4
- Drosophila 4
- Genome, Human 4
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1
Dynamic chromatin ATP-dependent chromatin remodeling machines /
Published 2007Table of Contents: “…Contents: ATP-dependent chromatin remodeling complexes -- ATP hydrolysis and nucleosome dynamics -- Mechanistic action -- Cellular function.…”
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2
Chromatin and transcription
Published 2007Table of Contents: “…Contents: Chromatin remodeling for transcription -- The RNA polymerase II transcription machinery -- Mediator of transcriptional regulation -- Atomic structure of RNA polymerase II and of a transcribing complex -- Structural basis of ribonucleotide addition and transcript elongation -- Structure of a complete pre-initiation complex.…”
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3
Introduction to chromatin structure
Published 2021Table of Contents: “…Contents: Chromatin and differential regulation of transcription -- Basic structure and properties of a nucleosome -- Current knowledge on higher order chromatin structures.…”
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4
Chromatin genes and disease
Published 2014Table of Contents: “…Contents: Chromatin genes and disease -- Epigenetics: the phenotype reflects the pattern of gene expression -- The role of chromatin in epigenetic regulation -- Epigenetic factors and their role in gene expression -- Human diseases involving epigenetic factors.…”
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5
Genome-wide organization of chromatin and the transcription machinery
Published 2014Table of Contents: “…Contents: Genomics of gene regulation -- Chromatin -- Canonical nucleosome organization around genes -- ChIP-exo mapping of sequence-specific transcription factors -- Genomic organization of transcription pre-initiation complexes.…”
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6
Chromatin architecture and alterations in the control of gene regulation
Published 2007Table of Contents: “…Contents: The chromatin environment -- Hierarchical organization of chromatin fibers within interphase chromosomes -- Milestone experiments that linked chromatin architecture and gene expression -- Proteins and processes that influence both chromatin fiber architecture and gene expression -- Core histone N-terminal tail domains -- Core histone sequence variants -- Linker histones -- Heterochromatin proteins -- Histone post-translational modifications -- The structurally dynamic nature of the genome in vivo and its relation to gene expression.…”
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7
Skin epigenetics how chromatin regulators orchestrate skin functions /
Published 2014Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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8
The basal transcription machinery for RNA polymerase II
Published 2014Table of Contents: “…Contents: The basal transcription machinery for RNA polymerase II -- DNA transcription -- Basal or general transcription factors -- Chromatin modifications -- RNA polymerase II -- TFIID -- Mediator.…”
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9
Eukaryotic gene regulation from chromatin to transcription to mRNA processing
Published 2007“…Eukaryotic gene regulation : from chromatin to transcription to RNA messenger processing…”
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10
Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /
Published 2017Table of Contents: “…Contents: PRC2 has an untargeted global function -- Chromatin immunoprecipitation (ChIP-seq) profiles -- H3K27 methylation -- The CBP/p300 acetylase complex -- The TRR complex (MLL3,4 in mammals) -- The DNA accessibility model -- How do PcG complexes repress? …”
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11
Histone dynamics, heritability and variants
Published 2022Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
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Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
12
Gene silencing in budding yeast
Published 2016Table of Contents: “…Contents: Gene silencing: an epigenetic phenomenon -- Chromatin remodeling: heterochromatin and euchromatin -- Silent chromatin in budding yeast: mating-type loci -- Silent information regulation: telomeric genes and Sir proteins.…”
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13
The molecular mechanism of X chromosome inactivation
Published 2016Table of Contents: “…Contents: X chromosome inactivation -- The X inactivation centre (Xic) -- Key role of the Xist locus -- Towards an understanding of Xist gene regulation in early mouse development -- Mechanisms regulating Xist RNA localisation within the inactive X chromosome territory -- Chromatin modification and gene silencing by Xist RNA.…”
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14
Enhancer malfunction in cancer
Published 2014Table of Contents: “…Contents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? …”
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15
Polycomb epigenetic mechanisms part 1 of 2, role of PcG complexes /
Published 2017Subjects: “…Chromatin. 94771…”
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16
Role of polycomb proteins in gene transcription, stem cell and human diseases
Published 2014Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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17
Legacy of Drosophila genetics female germline stem cells /
Published 2021Table of Contents: “…Contents: Lineage tracing -- Stem cell niches -- Germline stem cell niche in ovary -- Germline stem cell niche in testis – Dedifferentiation -- Stem cell signaling back to the niche -- Intestinal stem cells -- Stem cell chromatin.…”
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18
Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective
Published 2021Table of Contents: “…Contents: Chromatin dysregulation in cancer -- Features of epigenetic information in cells -- Mutated chromatin regulatory factors as tumor drivers -- Therapeutic rationale for the use of epigenetic drugs in oncology -- First generation epigenetic drugs: DNMT and HDAC inhibitors -- Novel therapeutic discoveries in oncology -- Biomarkers for patient selection.…”
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19
Genomics 101 an introduction to sequencing /
Published 2021Table of Contents: “…Contents: Sanger sequencing -- Fluorescent Sanger sequencing -- Whole genome sequencing -- Next generation sequencing -- Multiplexing -- Whole exome sequencing -- Transcriptome sequencing -- Chromatin immunoprecipitation sequencing.…”
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20
Epigenetic control by histone methylation
Published 2007Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
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Electronic Video