Search Results - "DNA methylation"
Suggested Topics within your search.
Suggested Topics within your search.
- DNA Methylation 21
- Epigenesis, Genetic 17
- genetics 9
- Epigenesis 6
- Chromatin 4
- DNA 4
- Genetic aspects 4
- Methylation 4
- Neoplasms 4
- Transcription, Genetic 4
- metabolism 4
- Gene Expression Regulation 3
- Genomic Imprinting 3
- Histones 3
- physiology 3
- Cancer 2
- Epigenetics 2
- Epigenomics 2
- Eukaryotic Cells 2
- Genetic transcription 2
- Histone Code 2
- Polycomb-Group Proteins 2
- Protein Processing, Post-Translational 2
- Transcription Factors 2
- Tumor Markers, Biological 2
- Acetylation 1
- Acetylesterase 1
- Age factors 1
- Aging 1
- Arabidopsis 1
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DNA methylation
Published 2014Table of Contents: “…Contents: Roles of DNA methylation -- Evolution of eukaryotic DNA methyltransferases -- Mechanism of action of DNA methyltransferases -- Specific loci targeting -- Histone modification -- Small interfering RNA.…”
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DNA methylation
Published 2007Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
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DNA methylation in cancer
Published 2011Table of Contents: “…Contents: DNA methylation in cancer -- Overview of DNA methylation in human cells -- Relationshoip of DNA methylation and chromatin structure -- Contribution of hypo/hypermethylation to tumorigenesis -- Mechanisms underlying altered DNA methylation patterns in cancer -- miRNAs as effectors and targets of aberrant DNA methylation in cancer -- Cancer methylation biomarkers -- Reversing DNA methylation in cancer therapy.…”
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DNA methylation, inflammation and cancer
Published 2010Table of Contents: “…Contents: DNA methylation in cancer in general -- Lung cancer -- Intestinal cancer -- Inflammation -- Method for genome-wide DNA methylation profiling -- Association of the Polycomb complex with DNA methylation in inflammation and cancer.…”
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Reversing DNA methylation pharmacologically
Published 2010Table of Contents: “…Contents: DNA Methylation as a target for disease therapy -- Azacitidine and Decitabine are "mechanistic" inhibitors of DNA methylation -- Clinical experience with DNA methylation inhibitors -- Translational science of biomarkers for DNA methylation inhibitor therapy -- Next generation drugs to inhibit DNA methylation.…”
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DNA methylation during development
Published 2010Table of Contents: “…Contents: Methylation of CpG islands in the genome -- Un-methylated/methylated genes -- DNA methylation and gene relationship -- Methylation of transcription start sites -- Methylation motifs -- What determines methylation state? …”
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DNA methylation and stem cells
Published 2010Table of Contents: “…Contents: Stem cells -- Pluripotent stem cells are extremely valuable for disease modeling and regenerative biology -- DNA methylation -- Stable epigenetic modification.…”
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Epigenetics a historical overview /
Published 2007Table of Contents: “…Contents: Introduction to epigenetics -- the leading pioneers in the field of epigenetics -- the basic features of development -- switching and heritability of gene activities -- DNA methylation -- epimutations -- differences between genetics and epigenetics -- genomic imprinting -- chromatin structure -- histone modifications -- the role of RNA in the epigenetic regulation of gene activity -- the bisulfite sequencing technique -- the epigenotype.…”
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DNA methylation and genome defense in Neurospora crassa
Published 2007Table of Contents: “…Contents: Control of DNA methylation -- repeat-induced point (RIP) mutation -- relationship of chromatin modifications and DNA methylation -- mutants that eliminate DNA methylation -- roles of histone H3 methyltransferase (DIM-5) and heterochromatin protein 1 (HP1) in DNA methylation -- indications of involvement of protein acetylation, methylation and phosphorylation in mechanism of DNA methylation -- propagation of DNA methylation and the associated silenced chromatin state.…”
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Epigenomics of complex disease
Published 2010Subjects: “…DNA Methylation. 109187…”
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Genomic Imprinting
Published 2011Subjects: “…DNA Methylation. 108709…”
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DNA methylation as a tumor marker implications for diagnosis, early detection and risk assessment /
Published 2010Subjects: “…DNA Methylation. 109174…”
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Proteins that bind methylated DNA
Published 2011Table of Contents: “…Contents: Introductory notions: distribution, abundance, and consequences of DNA methylation -- The methyl-binding proteins: who they are, how they were found -- What do the methyl-binding proteins do? …”
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DNA methylation changes in aging cells and tissues
Published 2011Table of Contents: “…Contents: Epigenetics -- Phenotypic variation -- DNA methylation -- Promoter CpG & Non CpG islands -- The methylome -- DNA methylation changes in aging -- Hypermethylation and silencing -- Methylation in normal colon vs. age -- Microarray analysis of aging human colon -- Methylation in aging human prostate -- Methylation vs. age in human right atrium -- MCAM analysis of aging mouse colon -- Pyro analysis of aging mouse colon -- Age related methylation along the GI tract -- Epigenetic mosaicism -- Human carcinogenesis as an epigenetic disease -- Changes in tissue function -- Tissue function consequences of DNA methylation changes in aging -- Epigenetic variation in human colon -- Susceptibility to DNA hypermethylation -- DNA hypermethylation and retrotransposons -- Genome-wide analysis of methylation proneness -- Genome architecture and the prediction of hypermethylation -- Repeat element distribution and age-related methylation -- Polycomb targets and hypermethylated genes in aging.…”
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Epigenetic biomarkers in cancer
Published 2012Table of Contents: “…Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.…”
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Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /
Published 2017Subjects: Get full text
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Role of polycomb proteins in gene transcription, stem cell and human diseases
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Epigenetics in age-related macular degeneration
Published 2017Subjects: Get full text
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Introduction to epigenetics
Published 2020Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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