Search Results - "DNA methylation"

DNA methylation

Table of Contents: “…Contents: Roles of DNA methylation -- Evolution of eukaryotic DNA methyltransferases -- Mechanism of action of DNA methyltransferases -- Specific loci targeting -- Histone modification -- Small interfering RNA.…”
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Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

DNA methylation

Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
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DNA methylation

Table of Contents: “…Contents: Roles of DNA methylation -- Evolution of eukaryotic DNA methyltransferases -- Mechanism of action of DNA methyltransferases -- Specific loci targeting -- Histone modification -- Small interfering RNA.…”
Get full text
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

DNA methylation

Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
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DNA methylation in plants by Vaniushin, B. F.

Subjects: An electronic book accessible through the World Wide Web; click to view

DNA methylation in cancer

Table of Contents: “…Contents: DNA methylation in cancer -- Overview of DNA methylation in human cells -- Relationshoip of DNA methylation and chromatin structure -- Contribution of hypo/hypermethylation to tumorigenesis -- Mechanisms underlying altered DNA methylation patterns in cancer -- miRNAs as effectors and targets of aberrant DNA methylation in cancer -- Cancer methylation biomarkers -- Reversing DNA methylation in cancer therapy.…”
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DNA methylation in cancer

Table of Contents: “…Contents: DNA methylation in cancer -- Overview of DNA methylation in human cells -- Relationshoip of DNA methylation and chromatin structure -- Contribution of hypo/hypermethylation to tumorigenesis -- Mechanisms underlying altered DNA methylation patterns in cancer -- miRNAs as effectors and targets of aberrant DNA methylation in cancer -- Cancer methylation biomarkers -- Reversing DNA methylation in cancer therapy.…”
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DNA methylation, inflammation and cancer

Table of Contents: “…Contents: DNA methylation in cancer in general -- Lung cancer -- Intestinal cancer -- Inflammation -- Method for genome-wide DNA methylation profiling -- Association of the Polycomb complex with DNA methylation in inflammation and cancer.…”
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Genomic Imprinting

Subjects: “…DNA Methylation.…”
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Reversing DNA methylation pharmacologically

Table of Contents: “…Contents: DNA Methylation as a target for disease therapy -- Azacitidine and Decitabine are "mechanistic" inhibitors of DNA methylation -- Clinical experience with DNA methylation inhibitors -- Translational science of biomarkers for DNA methylation inhibitor therapy -- Next generation drugs to inhibit DNA methylation.…”
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DNA methylation during development

Table of Contents: “…Contents: Methylation of CpG islands in the genome -- Un-methylated/methylated genes -- DNA methylation and gene relationship -- Methylation of transcription start sites -- Methylation motifs -- What determines methylation state? …”
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DNA methylation and stem cells

Table of Contents: “…Contents: Stem cells -- Pluripotent stem cells are extremely valuable for disease modeling and regenerative biology -- DNA methylation -- Stable epigenetic modification.…”
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Epigenomics of complex disease

Subjects: “…DNA Methylation.…”
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Epigenetics a historical overview / by Holliday, Robin, 1932-

Table of Contents: “…Contents: Introduction to epigenetics -- the leading pioneers in the field of epigenetics -- the basic features of development -- switching and heritability of gene activities -- DNA methylation -- epimutations -- differences between genetics and epigenetics -- genomic imprinting -- chromatin structure -- histone modifications -- the role of RNA in the epigenetic regulation of gene activity -- the bisulfite sequencing technique -- the epigenotype.…”
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DNA methylation and genome defense in Neurospora crassa

Table of Contents: “…Contents: Control of DNA methylation -- repeat-induced point (RIP) mutation -- relationship of chromatin modifications and DNA methylation -- mutants that eliminate DNA methylation -- roles of histone H3 methyltransferase (DIM-5) and heterochromatin protein 1 (HP1) in DNA methylation -- indications of involvement of protein acetylation, methylation and phosphorylation in mechanism of DNA methylation -- propagation of DNA methylation and the associated silenced chromatin state.…”
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DNA methylation patterns in mammals

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DNA methylation patterns in mammals

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DNA methylation, inflammation and cancer

Table of Contents: “…Contents: DNA methylation in cancer in general -- Lung cancer -- Intestinal cancer -- Inflammation -- Method for genome-wide DNA methylation profiling -- Association of the Polycomb complex with DNA methylation in inflammation and cancer.…”
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Reversing DNA methylation pharmacologically

Table of Contents: “…Contents: DNA Methylation as a target for disease therapy -- Azacitidine and Decitabine are "mechanistic" inhibitors of DNA methylation -- Clinical experience with DNA methylation inhibitors -- Translational science of biomarkers for DNA methylation inhibitor therapy -- Next generation drugs to inhibit DNA methylation.…”
Get full text
Series

DNA methylation during development

Table of Contents: “…Contents: Methylation of CpG islands in the genome -- Un-methylated/methylated genes -- DNA methylation and gene relationship -- Methylation of transcription start sites -- Methylation motifs -- What determines methylation state? …”
Get full text
Series