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Regulation of synaptic plasticity by astroglia

Table of Contents: “…Contents: Astroglia are the most abundant type of glial cells -- Their role has recently emerged as an active contributor to neural function -- The underlying mechanisms remain poorly understood -- Astrocytes release D-serine in a Ca2+ dependent manner -- Interference with this release reduces activation of synaptic NMDA receptors -- This in turn could severely impair induction of long-term synaptic potentiation -- Astroglia thus may play a fundamental role in mechanisms of memory formation in the brain.…”
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Regulation of synaptic plasticity by astroglia

Table of Contents: “…Contents: Astroglia are the most abundant type of glial cells -- Their role has recently emerged as an active contributor to neural function -- The underlying mechanisms remain poorly understood -- Astrocytes release D-serine in a Ca2+ dependent manner -- Interference with this release reduces activation of synaptic NMDA receptors -- This in turn could severely impair induction of long-term synaptic potentiation -- Astroglia thus may play a fundamental role in mechanisms of memory formation in the brain.…”
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Regulation of synaptic plasticity by astroglia

Table of Contents: “…Contents: Astroglia are the most abundant type of glial cells -- Their role has recently emerged as an active contributor to neural function -- The underlying mechanisms remain poorly understood -- Astrocytes release D-serine in a Ca2+ dependent manner -- Interference with this release reduces activation of synaptic NMDA receptors -- This in turn could severely impair induction of long-term synaptic potentiation -- Astroglia thus may play a fundamental role in mechanisms of memory formation in the brain.…”
Get full text
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