Search Results - "cell adhesion"

Pleiotropic and epistatic genes in sickle cell anemia

Table of Contents: “…Contents: Determination of pleiotropic genes -- Search for polymorphic genes among the pleiotropic genes as candidates for epistasis -- Known epistatic effects -- Kidney pathology in sickle cell disease -- Renal disease epidemiology -- Panoply of transgenic mice -- Involvement of metabolic pathways in constitutive chronic kidney damage in Tx mice -- Hypoxia -- Mediators of oxidative stress -- Up and down regulated genes -- HO- 1 histopathology -- The effect of sickle red blood cell adhesion on gene expression in PAF pre-treated microcirculatory bed -- Von Willebrand factor (vWF) and sickle cell anemia -- vWF, shear stress and sickle cell anaemia -- Epistatic genes may open new therapeutic strategies for SS disease -- PAF induces the up-regulation of a number of genes that have the capacity of protecting the endothelium, stem cells and other hematopoetic precursors.…”
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