Search Results - "liver disease"

Drug-induced liver disease an update for 2010 /

Table of Contents: “…Contents: DILD overview -- Pathology of DILD -- Incidence of DILI -- Spectrum of DILI -- Hepatic adverse event nomenclature: liver injury -- Causes of acute liver failure -- Biochemical patterns of liver injury -- Clinical features of acute hepatocellular DILD -- Cholestatic DILI -- Drugs associated with chronic autoimmune type hepatitis -- Drugs associated with hepatic fibrosis/cirrhosis -- Drug-induced steatohepatitis -- Miscellaneous forms of chronic DILD -- Prevalence of hepatic enzyme elevations with various drugs -- Possible mechanisms of drug adaptation (drug tolerance) -- Drugs that have caused fulminant hepatic failure -- FDA stopping rule for liver injury in drug development -- Mortality from acute DILD -- Hy's law -- Causes of drug induced ALF leading to liver transplant -- Major regulatory actions due to DILI -- Drug related and idiosyncratic mechanisms of cellular injury in DILI -- Drug metabolism and risk of DILI -- Acetaminophen association with DILI -- Host risk factors for DILD -- Possible genetic predisposition to DILD -- Alcohol and other agents that affect drug hepatotoxicity -- Medicating patients with underlying liver disease -- The importance of accurately diagnosing DILI -- Improving the causality assessment process using scoring systems -- Preventing drug induced liver disease -- Treating DILD -- Herbal agents (problems and use) -- DILI risk vs. benefit considerations -- Future directions in DILD.…”
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Drug-induced liver injury importance, epidemiology, and mechanisms of DILI /

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Drug-induced liver injury importance, epidemiology, and mechanisms of DILI /

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Drug-induced liver injury risk factors and drug development in DILI /

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Drug-induced liver injury HDS, diagnosing, treating and preventing DILI /

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Drug-induced liver injury risk factors and drug development in DILI /

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Drug-induced liver injury HDS, diagnosing, treating and preventing DILI /

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