Published 2011
Table of Contents:
“…(Publisher-supplied data) Part I Basic Concepts of Drug Metabolism and Disposition -- The Progression of Drug Metabolism -- Common Biotransformation Reactions -- Metabolic Activation of Organic Functional Groups Utilized in Medicinal Chemistry -- Drug Metabolizing Enzymes, Transporters and Drug-Drug Interactions -- Experimental Models of Drug Metabolism and Disposition -- Principles of Pharmacokinetics: Predicting Human Pharmacokinetics -- Drug Metabolism Research as an Integral Part of the Drug Discovery and Development Processes -- Part II
Mass Spectrometry in Drug Metabolism: Principles and Common Practice -- Theory and Instrumentation of
Mass Spectrometry -- Common Liquid Chromatography-
Mass Spectrometry (LC-MS) Methodology for Metabolite Identification -- Mass Spectral Interpretation -- Techniques to Facilitate the Performance of
Mass Spectrometry: Sample Preparation, Liquid Chromatography and Non-Mass Spectrometric Detection -- Part III Applications of New LC/MS Techniques in Drug Metabolism and Disposition -- Quantitative In Vitro ADME Assays using LC-MS as a Part of Early Drug Metabolism Screening -- High Resolution
Mass Spectrometry and Drug Metabolite Identification -- Distribution Studies of Drugs and Metabolites in Tissue by Mass Spectrometric Imaging -- Use of Triple Quadrupole-Linear Ion Trap
Mass Spectrometry as a Single LC/MS Platform in Drug Metabolism and Pharmacokinetics Studies -- Quantitative Drug Metabolism with Accelerator
Mass Spectrometry -- Standard-Free Estimation of Metabolite Levels Using Nanospray
Mass Spectrometry: Current Statutes and Future Directions -- Profiling and Characterization of Herbal Medicine and their Metabolites using LC-MS -- Liquid Chromatography
Mass Spectrometry Bioanalysis of Proteins in Biological Matrices --
Mass Spectrometry in the Analysis of DNA, Protein, Peptide, and Lipid Biomarkers of Oxidative Stress -- LC-MS in Endogenous Metabolite Profiling and Small Molecule Biomarker Discovery.…”
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