Search Results - "stem cell"

Intestinal stem cell-mediated repair in Drosophila part 1 of 2 /

Table of Contents: “…Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs) -- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration -- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes -- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs -- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division -- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.…”
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Intestinal stem cell-mediated repair in Drosophila Part 2 of 2 /

Table of Contents: “…Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs) -- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration -- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes -- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs -- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division -- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.…”
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