Search Results - Drugs

Enzymology in drug discovery part 1 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
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Enzymology in drug discovery part 2 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
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Enzymology in drug discovery part 1 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
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Enzymology in drug discovery part 2 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
Get full text
Series

Enzymology in drug discovery part 1 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
Get full text
Series

Enzymology in drug discovery part 2 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
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Evaluation of enzyme inhibitors in drug discovery a guide for medicinal chemists and pharmacologists / by Copeland, Robert Allen

Table of Contents: “…Machine generated contents note: Foreword.Preface.Acknowledgments.1. Why Enzymes as Drug Targets?1.1 Enzymes Are Essentials for Life.1.2 Enzyme Structure and Catalysis.1.3 Permutations of Enzyme Structure During Catalysis.1.4 Other Reasons for Studying Enzymes.1.5 Summary.References.2. …”
An electronic book accessible through the World Wide Web; click to view

Evaluation of enzyme inhibitors in drug discovery a guide for medicinal chemists and pharmacologists / by Copeland, Robert Allen

Subjects: An electronic book accessible through the World Wide Web; click to view