Search Results - "amplifier"

Molecular identification of the CRAC channel

Table of Contents: “…Contents: Background on Calcium signaling and ion channels in the immune system, role of CRAC channels in lymphocyte activation -- Discovery of Stim and STIM1 by RNA interference screen in Drosophila S2 cells -- Stim as an ER Calcium sensor and as a messenger to the plasma membrane -- Genome-wide RNA interference screen and the discovery of Orai -- Amplifying CRAC current by co-expression of Stim and Orai -- Molecular identification of CRAC channels by altered ion selectivity in a mutant of Orai -- How does the CRAC channel activate?…”
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