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Management of MDR and XDR TB

Table of Contents: “…Contents: Management of multi drug resistance (MDR) and extensive drug resistance (XDR) TB -- Management of TB before era of drug treatment -- Surgery for TB -- Drug treatment was introduced from 1943-1963 -- Rifampicin (1963) -- Timeline: discovery of drugs for TB -- Emergence of totally drug resistant TB -- Epidemiology -- Outcomes of MDR-TB treatment -- Survival curve of HIV patients with XDR TB -- Current drug treatment -- Treatment outcome in several cohorts -- Death rates in several cohorts -- Current approach for treatment of MDR/XDR TB -- WHO's programmatic management of DR TB -- Treatment recommendations -- Group 1: oral first-line agents -- Group 2: fluoroquinolones -- Group 3: injectables -- Group 4: less-effective anti-TB drugs -- Group 5: less-effective or clinical data sparse drugs -- Future drug treatment -- New compounds -- Bedaquiline (TMC207) -- The nitroimidazoles -- Thioridazine -- NC-001 (PA-824, moxifloxacine, PZA) -- Dreams and realities for the future of TB treatment.…”
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Management of MDR and XDR TB

Table of Contents: “…Contents: Management of multi drug resistance (MDR) and extensive drug resistance (XDR) TB -- Management of TB before era of drug treatment -- Surgery for TB -- Drug treatment was introduced from 1943-1963 -- Rifampicin (1963) -- Timeline: discovery of drugs for TB -- Emergence of totally drug resistant TB -- Epidemiology -- Outcomes of MDR-TB treatment -- Survival curve of HIV patients with XDR TB -- Current drug treatment -- Treatment outcome in several cohorts -- Death rates in several cohorts -- Current approach for treatment of MDR/XDR TB -- WHO's programmatic management of DR TB -- Treatment recommendations -- Group 1: oral first-line agents -- Group 2: fluoroquinolones -- Group 3: injectables -- Group 4: less-effective anti-TB drugs -- Group 5: less-effective or clinical data sparse drugs -- Future drug treatment -- New compounds -- Bedaquiline (TMC207) -- The nitroimidazoles -- Thioridazine -- NC-001 (PA-824, moxifloxacine, PZA) -- Dreams and realities for the future of TB treatment.…”
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Series

Management of MDR and XDR TB

Table of Contents: “…Contents: Management of multi drug resistance (MDR) and extensive drug resistance (XDR) TB -- Management of TB before era of drug treatment -- Surgery for TB -- Drug treatment was introduced from 1943-1963 -- Rifampicin (1963) -- Timeline: discovery of drugs for TB -- Emergence of totally drug resistant TB -- Epidemiology -- Outcomes of MDR-TB treatment -- Survival curve of HIV patients with XDR TB -- Current drug treatment -- Treatment outcome in several cohorts -- Death rates in several cohorts -- Current approach for treatment of MDR/XDR TB -- WHO's programmatic management of DR TB -- Treatment recommendations -- Group 1: oral first-line agents -- Group 2: fluoroquinolones -- Group 3: injectables -- Group 4: less-effective anti-TB drugs -- Group 5: less-effective or clinical data sparse drugs -- Future drug treatment -- New compounds -- Bedaquiline (TMC207) -- The nitroimidazoles -- Thioridazine -- NC-001 (PA-824, moxifloxacine, PZA) -- Dreams and realities for the future of TB treatment.…”
Get full text
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