Search Results - "epigenetics"

DNA methylation

Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
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