Use of DNA pooling in large-scale association studies

Use of DNA pooling in large-scale association studies

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Bibliographic Details
Other Authors: Sham, Pak (Pak C.) (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2004.
Series:Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology I : fundamentals, theory, practice and latest developments.
Subjects:
Genetic Predisposition to Disease > epidemiology.
Online Access:https://hstalks.com/bs/37/
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Table of Contents:
  • Contents: Principles of DNA pooling
  • The cost benefit
  • Getting the quantification right
  • SNaPshot
  • Estimating and incorporating measurement error
  • Consequences of differential amplification
  • Pool construction vs. genotyping errors
  • Determining optimal design
  • Family designs
  • Stratified designs
  • Design for quantitative traits
  • Methods for statistical analysis
  • Case study: ADHD
  • Approaches to haplotype analysis in DNA pooling
  • Recommendations.

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