Extracellular domain structures from calcium-sensing and GABA(B) receptors

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Bibliographic Details
Other Authors:	Fan, Qing R. (Speaker)
Format:	Electronic Video
Language:	English
Published:	London : Henry Stewart Talks, 2019.
Series:	Henry Stewart talks. Biomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease.
Subjects:	Amino acids > Receptors. Calcium > Receptors. Cellular signal transduction. G proteins > Receptors. Binding Sites. GABA-B Receptor Agonists. GABA-B Receptor Antagonists. Protein Conformation. Receptors, Calcium-Sensing > chemistry. Receptors, Calcium-Sensing > metabolism. Receptors, GABA-B > chemistry. Receptors, GABA-B > metabolism. Receptors, G-Protein-Coupled.
Online Access:	https://hstalks.com/bs/4009/ Series
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Table of Contents:

Contents: Crystal structures of human GABA(B) receptor extracellular domain in multiple functional states
Agonist vs. antagonist recognition
Identification of novel heterodimer interface associated with receptor activation
Crystal structures of human CaSR in the inactive and active conformations
Discovery of L-amino acids as orthosteric agonists of CaSR
Identification of Ca2+ and PO43 binding sites in CaSR
Universal activation mechanism of class C GPCRs.

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