Structural and mechanistic insights into the neurotensin receptor

Structural and mechanistic insights into the neurotensin receptor

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Bibliographic Details
Other Authors: Grisshammer, R. K. (Reinhard K.) (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2019.
Series:Henry Stewart talks. Biomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease.
Subjects:
Cellular signal transduction.
G proteins > Receptors.
Molecular structure.
Neurotensin.
Molecular Dynamics Simulation.
Neurotensin > chemistry.
Neurotensin > metabolism.
Protein Conformation.
Receptors, G-Protein-Coupled.
Receptors, Neurotensin > chemistry.
Receptors, Neurotensin > metabolism.
Online Access:https://hstalks.com/bs/3998/
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Table of Contents:
  • Contents: G protein-coupled receptors
  • Neurotensin receptor
  • Peptide agonist neurotensin tools for crystallization of membrane proteins
  • Conformational thermostabilization
  • Crystal structure of NTSR1-GW5
  • Binding mode of neurotensin
  • Crystal structures of NTSR1-ELF & NTSR1-LF-prerequisites for G protein activation
  • Crystal structure of NTSR1-EL
  • Constitutive activity
  • Molecular dynamics simulations.

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