Chaperonin-mediated protein folding part 2 /

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Bibliographic Details
Other Authors: Horwich, Arthur (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2012.
Series:Henry Stewart talks. Biomedical & life sciences collection.
Subjects:
Online Access:https://hstalks.com/bs/2389/
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Table of Contents:
  • Contents: Chaperonin-mediated protein folding by GroEL/GroES
  • Folding of newly-translated protein
  • Currently known Molecular chaperones (including the Heat shock protein Hsp group)
  • Recognition of non native proteins by Hsps and formation of aggregates
  • Aggregates and neurodegenerative disease -The discovery of the chaperonin-mediated folding
  • The structure of the GroES/GroeEL chaperonin class of molecular chaperones
  • The steps of polypeptide binding and folding
  • The action of ATP binding and hydrolysis in driving the rings of the machine through cycles of binding and release cycle.