The role of phosphorylation in mediating cellular responses to DNA damage the ATM-mediated DNA damage response /

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Bibliographic Details
Other Authors: Shiloh, Yosef (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2011.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein phosphorylation.
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Online Access:https://hstalks.com/bs/1889/
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Table of Contents:
  • Contents: Endogenous DNA damage in mammalian cells
  • DSB repair pathways
  • Cellular responses to DNA damage
  • Genomic instability syndromes
  • Ataxia-telangiectasia
  • The ATM protein
  • ATM-mediated DNA damage responses
  • A SPIKE map
  • Defective repair of DNA double strand breaks
  • Allowing repair to happen within chromatin
  • DNA damage response and the ubiquitin family
  • Players in ubiquitin-related processes
  • Phosphoproteome dynamics after DNA damage
  • Functional networks of phosphorylated proteins
  • Overlap between Ub, ATM and phosporylation
  • Functional screens for novel DDR players.