Structure and mechanisms of protein phosphatases

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Bibliographic Details
Other Authors: Barford, David (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2010.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein phosphorylation.
Subjects:
Online Access:https://hstalks.com/bs/1883/
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Table of Contents:
  • Contents: Reversible protein phosphorylation
  • Classification of protein phosphatases
  • Protein tyrosine phosphatase family, structure of PTP1B, catalytic mechanism, basis for pTyr specificity, recognition of IRK, regulation by ROS and cyclic sulphenamide
  • Dual specificity phosphatases
  • Eya protein tyrosine phosphatases
  • PPP family of Ser/Thr phosphatases, structure of PP1, catalytic mechanism, inhibition by okadaic acid and microcystin, targeting subunits, PP2A, PP2B, PP5
  • PPM family of Ser/Thr phosphatases, structure, catalytic mechanism
  • Summary.