Protein Tyrosine Phosphatases

Protein Tyrosine Phosphatases

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Bibliographic Details
Other Authors: Dixon, Jack Edward, 1943- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2010.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein phosphorylation.
Subjects:
Phosphorylation.
Protein Tyrosine Phosphatases.
Online Access:https://hstalks.com/bs/1884/
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Table of Contents:
  • Contents: Kinases and phosphatases
  • Ways to remove phosphate from proteins
  • Class I Cys-based PTPs
  • Phosphatase families
  • Mutational analysis of PTP-1
  • Sequences at active site
  • Phospho-enzyme intermediate
  • pH stability of phosphoprotein phosphate
  • Site-directed mutational analysis of VHR
  • How PTPs share a catalytic active site motif
  • Sequences of phosphatases
  • The bacterial Yop 2b phosphatase activity
  • Bacterial growth in the spleen of mice
  • Yop 2b in eukaryotic macrophages
  • Interaction between Yersinia and a target cell
  • Phosphatases as tumor suppressor genes
  • PTEN and myotubularin structure
  • PTEN-10q23.3
  • Frequency of PTEN mutations
  • Kinetic constants of dual-specificity phosphates
  • How PTEN is a "lipid" phosphatase
  • How PTEN might inhibit cell survival
  • Effect of PTEN overexpression on PIP3 production
  • Effect of PTEN expression on PI 3-kinase activation
  • Inositol phosphatase activity of PTEN
  • PTEN tumor suppressor activity
  • Key PTEN and PIP3 researchers -RNA interference in C.elegans
  • RNA interference protocol for fly S2 cells
  • Mammalian, C.elegans and fly signaling cascade
  • How PTEN inhibits Akt activity
  • The active site pocket of PTEN
  • Sequence alignment of PTEN catalytic site.

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