Protein Tyrosine Phosphatases

Protein Tyrosine Phosphatases

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Bibliographic Details
Other Authors: Dixon, Jack Edward, 1943- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2010.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein phosphorylation.
Subjects:
Phosphorylation.
Protein Tyrosine Phosphatases.
Online Access:https://hstalks.com/bs/1884/
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028 5 0 |a 2706  |b Henry Stewart Talks 
035 |a (UkLoHST)1884 
040 |a UkLoHST  |b eng  |c UkLoHST 
100 1 |a Dixon, Jack Edward,  |d 1943-  |4 spk  |9 108940 
245 1 0 |a Protein Tyrosine Phosphatases  |h [electronic resource] /  |c Jack Dixon. 
260 |a London :  |b Henry Stewart Talks,  |c 2010. 
300 |a 1 online resource (1 streaming video file (45 min.) :  |b color, sound). 
490 1 |a Protein phosphorylation,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Kinases and phosphatases -- Ways to remove phosphate from proteins -- Class I Cys-based PTPs -- Phosphatase families -- Mutational analysis of PTP-1 -- Sequences at active site -- Phospho-enzyme intermediate -- pH stability of phosphoprotein phosphate -- Site-directed mutational analysis of VHR -- How PTPs share a catalytic active site motif -- Sequences of phosphatases -- The bacterial Yop 2b phosphatase activity -- Bacterial growth in the spleen of mice -- Yop 2b in eukaryotic macrophages -- Interaction between Yersinia and a target cell -- Phosphatases as tumor suppressor genes -- PTEN and myotubularin structure -- PTEN-10q23.3 -- Frequency of PTEN mutations -- Kinetic constants of dual-specificity phosphates -- How PTEN is a "lipid" phosphatase -- How PTEN might inhibit cell survival -- Effect of PTEN overexpression on PIP3 production -- Effect of PTEN expression on PI 3-kinase activation -- Inositol phosphatase activity of PTEN -- PTEN tumor suppressor activity -- Key PTEN and PIP3 researchers -RNA interference in C.elegans -- RNA interference protocol for fly S2 cells -- Mammalian, C.elegans and fly signaling cascade -- How PTEN inhibits Akt activity -- The active site pocket of PTEN -- Sequence alignment of PTEN catalytic site. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Phosphorylation.  |9 108941 
650 2 |a Protein Tyrosine Phosphatases.  |9 108942 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Protein phosphorylation.  |9 108943 
856 4 0 |u https://hstalks.com/bs/1884/ 
856 4 2 |u https://hstalks.com/bs/p/531/  |3 Series 
999 |c 215643  |d 215642 

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