The pRB/E2F pathway

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Bibliographic Details
Other Authors: Lees, Jacqueline (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2009.
Series:Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate.
Subjects:
Online Access:https://hstalks.com/bs/1254/
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028 5 0 |a 2338  |b Henry Stewart Talks 
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040 |a UkLU-K  |b eng  |c UkLU-K 
100 1 |a Lees, Jacqueline.  |4 spk  |9 113610 
245 1 4 |a The pRB/E2F pathway  |h [electronic resource] /  |c Jacqueline Lees. 
260 |a London :  |b Henry Stewart Talks,  |c 2009. 
300 |a 1 online resource (1 streaming video file (33 min.) :  |b color, sound). 
490 1 |a The cell division cycle : controlling when and where cells divide and differentiate,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: The E2F transcription factors control cell cycle entry -- The pRB/E2F pathway -- pRB and E2F are both families of proteins -- Differential roles of the pocket proteins -- Repression and activation of E2F target genes is regulated by distinct E2F complexes -- Rb mutant mice -- Inhibition of the activating E2Fs is key to pRB's tumor suppressive activity -- The activating E2Fs can also induce apoptosis and senescence genes in tumor cells -- Role of pRB-E2F in DNA damage response -- pRB contributes to the activation of pro-apoptotic genes in response to DNA damage. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Cell Cycle Proteins.  |9 113611 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Cell division cycle : controlling when and where cells divide and differentiate.  |9 113612 
856 4 0 |u https://hstalks.com/bs/1254/ 
856 4 2 |u https://hstalks.com/bs/p/381/  |3 Series 
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