Geometric regulation of kinetochore orientation

Geometric regulation of kinetochore orientation

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Bibliographic Details
Other Authors: Watanabe, Yoshinori, 1961- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2009.
Series:Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate.
Subjects:
Cell Cycle.
Kinetochores.
Online Access:https://hstalks.com/bs/1275/
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Table of Contents:
  • Contents: The cell cycle
  • Aurora B-dependent destabilization
  • The attachment is stabilized under tension
  • Tension-dependent reorientation
  • Kinetochore geometry
  • Organization of centromeres
  • Budding yeast
  • Two models to account for the mono-polar attachment at meiosis I
  • Rec8 vs. Rad21 at the centromere
  • Cohesion-mediated kinetochore orientation model
  • Is the central core cohesion defective in moa1Δ?
  • A lacO array in the core centromere
  • Excision of core centromeres
  • Cohesion at core centromeres depends on Moa1 as well as Rec8
  • Cohesion at core centromeres is disrupted at prophase II
  • Centromeric resolution in mitosis
  • Core centromere is intrinsically prevented from establishment of cohesion
  • Artificial tether at the core centromere
  • Opposite effects of tethers at the core and peri-centromeric regions.

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