The spindle checkpoint

The spindle checkpoint

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Bibliographic Details
Other Authors: Hardwick, Kevin G. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2009.
Series:Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate.
Subjects:
Cell Cycle.
Mitosis.
Online Access:https://hstalks.com/bs/1266/
Series
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245 1 4 |a The spindle checkpoint  |h [electronic resource] /  |c Kevin G. Hardwick. 
260 |a London :  |b Henry Stewart Talks,  |c 2009. 
300 |a 1 online resource (1 streaming video file (54 min.) :  |b color, sound). 
490 1 |a The cell division cycle : controlling when and where cells divide and differentiate,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Cell cycle checkpoints -- The metaphase to anaphase transition -- The spindle checkpoint -- What do cells monitor? -- Unattached kinetochores -- Lack of tension -- Checkpoint components -- Budding yeast genetic screens -- Microcolony assay -- Localisation of Mad proteins -- Checkpoint proteins are all recruited kinetochores -- Role of kinetochores -- Global signaling -- Identification of Cdc20 as the checkpoint effector -- CdC20-APC -- FRAP -- Mad1/Mad2 complex as a template -- The anaphase promoting complex (APC) -- How is anaphase onset inhibited -- Mad2 and Mad3 bind mitotic APC -- Separase regulation by securin -- Error correction -- Chromosomal passenger proteins -- How to sense a lack of tension? -- Checkpoint role(s) of Aurora kinase (Ipl1) -- Checkpoint silencing -- Disease relevance -- Future directions. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Cell Cycle.  |9 113595 
650 2 |a Mitosis.  |9 113596 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Cell division cycle : controlling when and where cells divide and differentiate.  |9 113597 
856 4 0 |u https://hstalks.com/bs/1266/ 
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