Chromosome bi-orientation in yeast

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Bibliographic Details
Other Authors:	Stark, Mike (Speaker), Tanaka, Tomo (Speaker)
Format:	Electronic Video
Language:	English
Published:	London : Henry Stewart Talks, 2022.
Series:	Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate.
Subjects:	Saccharomyces cerevisiae > Genetics. Yeast fungi > Genetics. Aneuploidy. Aurora Kinases. Cell Cycle. Chromatids. Chromosomes, Fungal. Kinetochores. Microtubules. Saccharomyces cerevisiae > genetics. Saccharomyces cerevisiae > physiology. Spindle Apparatus > physiology.
Online Access:	https://hstalks.com/bs/1262/ Series
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Table of Contents:

Contents: What is chromosome biorientation and why is it important?
Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy
Modes of sister chromatid attachment to spindle microtubules
The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation
Monitoring sister centromeres on individual yeast chromosomes
Kinetochore capture
Achieving chromosome bi-orientation: mechanisms
Geometry-dependent mechanism or a correction mechanism?
Yeast Ipl1p kinase
Chromosomes fail to bi-orient with high frequency in Ipl1 mutants
How might Ipl1p kinase promote bi-orientation?
Yeast chromosomes can bi-orient without the need for back-to-back geometry
How does Ipl1p kinase promote bi-orientation?
The yeast chromosomal passenger complex
Models for tension-sensing
What are the targets of Ipl1p kinase at the kinetochore?
Model for Ipl1 / Aurora function in promoting bi-orientation
Does Aurora B have similar targets in other organisms?
Other components required for bi-orientation
Ipl1p kinase may coordinate chromosome bi-orientation and spindle checkpoint activation.

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