Global analysis of gene translation

Global analysis of gene translation

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Bibliographic Details
Other Authors: Tofilon, Philip J. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2009.
Series:Henry Stewart talks. Biomedical & life sciences collection. Microarrays : their design and use.
Subjects:
Gene Expression.
Microarray Analysis.
Oligonucleotide Array Sequence Analysis.
Protein Biosynthesis > radiation effects.
Online Access:https://hstalks.com/bs/1201/
Series
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028 5 0 |a 2217  |b Henry Stewart Talks 
035 |a (UkLoHST)1201 
035 |a (UkLU-K)001103538 
040 |a UkLU-K  |b eng  |c UkLU-K 
100 1 |a Tofilon, Philip J.  |4 spk  |9 113679 
245 1 0 |a Global analysis of gene translation  |h [electronic resource] /  |c Philip Tofilon. 
260 |a London :  |b Henry Stewart Talks,  |c 2009. 
300 |a 1 online resource (1 streaming video file (38 min.) :  |b color, sound). 
490 1 |a Microarrays : their design and use,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Radiation-induced gene expression has long been considered to play a role in determining cellular radioresponse -- Analyses of single genes and whole genomes indicate that radiation-induced changes at the mRNA level do not correlate with changes in corresponding proteins -- Microarray analysis of polysome-bound RNA indicates that radiation modifies the translational activity of mRNA subpopulations, which correlates with protein products -- Gene translation is considerably more susceptible to radiation-induced changes than is the transcriptome -- Defining the genes whose translation is modified by radiation may provide an approach for identifying critical proteins and pathways that serve as determinants of radiosensitivity. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Gene Expression.  |9 113680 
650 2 |a Microarray Analysis.  |9 113681 
650 2 |a Oligonucleotide Array Sequence Analysis.  |9 113682 
650 2 |a Protein Biosynthesis  |x radiation effects.  |9 113683 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Microarrays : their design and use.  |9 113684 
856 4 0 |u https://hstalks.com/bs/1201/ 
856 4 2 |u https://hstalks.com/bs/p/382/  |3 Series 
999 |c 216596  |d 216595 

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