Drug induced liver injury a clinical perspective /

Drug induced liver injury a clinical perspective /

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Bibliographic Details
Other Authors: Navarro, Victor J. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2009.
Series:Henry Stewart talks. Biomedical & life sciences collection. Non-clinical testing for toxicity of pharmaceuticals.
Subjects:
Drug Toxicity.
Toxicity Tests.
Online Access:https://hstalks.com/bs/1346/
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Table of Contents:
  • Contents: Definition of drug induced liver injury (DILI)
  • Types and mechanisms of DILI
  • Safety withdrawals
  • Signals of DILI in drug development
  • Epidemiology of DILI
  • Clinical patterns
  • Hepatocellular liver injury
  • Cholestatic liver injury
  • What comprises liver injury?
  • Adaptation to injury
  • Toxicity grading in clinical trials
  • Jaundice
  • Common signatures of DILI
  • Susceptibility factors for DILI
  • Key elements in diagnosis
  • Causality assessment tools
  • Management of DILI
  • Monitoring in clinical practice.

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