Signaling by innate immune receptors
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| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2009.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/1295/ Series |
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Table of Contents:
- Contents: Understanding how receptors involved in the detection of infection (TLRs and NLRs) and inflammation (TNFRs) mediated their biological effects
- The activation of innate immune responses depends on recognition of infectious organisms (bacteria, fungi, viruses, etc.) by specialized pattern recognition receptors that include the large families of membrane-associated TLRs and cytosolic NLRs
- Signaling mechanisms used by TLRs and NLRs, as well as by TNFRs that respond to pro-inflammatory cytokines
- Their biological effects include the production of cytokines, chemokines, anti-microbial peptides and enzymes that generate inflammatory mediators and reactive oxygen.
NOD-like receptors in innate immunity and inflammatory disease