Animal models to explore cardiovascular disease

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Bibliographic Details
Other Authors: Merkel, Martin (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2008.
Series:Henry Stewart talks. Biomedical & life sciences collection. Genetics of cardiovascular disease.
Subjects:
Online Access:https://hstalks.com/bs/1055/
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Table of Contents:
  • Contents: Atherosclerosis is a complex disease involving several different molecular and cellular mechanisms in its pathogenesis
  • For its experimental investigation, usually higher animals as mammals need to be employed
  • Here, the animal models currently used in atherosclerotic research are reviewed und their respective advantages and disadvantages are depicted
  • Use of inbred mouse strains and different genetically modified mice
  • The main disparities between mouse and human lipid metabolism
  • Considerations and techniques to create useful animal models.