Predicting TSE transmission

Saved in:
Bibliographic Details
Other Authors: Manson, Jean (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2008.
Series:Henry Stewart talks. Biomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi.
Subjects:
Online Access:https://hstalks.com/bs/952/
Series
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000ngm a2200000 a 4500
001 HST1911_1_2
003 UkLoHST
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 080121s2008 enk|||||||||||s|||v|eng d
028 5 0 |a 1911  |b Henry Stewart Talks 
035 |a (UkLoHST)952 
035 |a (UkLU-K)AC000395881 
040 |a UkLU-K  |b eng  |c UkLU-K 
100 1 |a Manson, Jean.  |4 spk  |9 112860 
245 1 0 |a Predicting TSE transmission  |h [electronic resource] /  |c Jean Manson. 
260 |a London :  |b Henry Stewart Talks,  |c 2008. 
300 |a 1 online resource (1 streaming video file (41 min.) :  |b color, sound). 
490 1 |a Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: The TSEs continue to pose a problem to animal and human health -- The vCJD epidemic appears to be in decline but new risks of human to human transmission are now apparent -- Chronic wasting disease is a major problem currently in the US although its presence has not yet been detected in Europe -- Predicting and preventing transmission of disease requires an understanding of the routes of transmission within and between animals and the host factors which determine susceptibility -- We have studied natural disease and both in vivo and in vitro model systems to unravel the basic mechanisms of disease -- PrP protein has a central role in the outcome disease and mutations and polymorphisms in host PrP can profoundly alter the host's susceptibility to a TSE agent -- Precisely how host PrP influences the outcome of disease has not been established -- Both mutations and glycosylation can profoundly influence transmission both within and between species. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Amyloid.  |9 112861 
650 2 |a Prions.  |9 112862 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi.  |9 112863 
856 4 0 |u https://hstalks.com/bs/952/ 
856 4 2 |u https://hstalks.com/bs/p/282/  |3 Series 
999 |c 216431  |d 216430