Admixture mapping
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| Other Authors: | |
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| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2007.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology II : latest developments.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/606/ Series |
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Table of Contents:
- Contents: Applications of statistical modelling of population admixture
- Genetic and environmental explanations for ethnic differences in disease risk
- Methods for finding genes that influence complex traits
- Exploiting admixture to map genes
- Statistical power of admixture mapping
- Advantages of admixture mapping in comparison with other approaches to finding disease susceptibility genes
- Methodological problems of extending linkage analysis of a cross to admixed human populations
- Statistical methods that allow linkage analysis of a cross to be extended to admixed humans
- Model for stochastic variation of ancestry on chromosomes inherited from an admixed parent
- Multipoint inference of ancestry at marker loci from genotypes
- Null hypothesis as graphical model
- Statistical approach to model fitting and hypothesis testing
- The score test algorithm
- Other model diagnostics: "Bayesian p-values"
- How many markers are required for genome-wide admixture mapping?
- Panels of ancestry-informative markers
- Other applications of statistical modelling of admixture.
QTL association mapping