Admixture mapping

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Bibliographic Details
Other Authors: McKeigue, Paul (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology II : latest developments.
Subjects:
Online Access:https://hstalks.com/bs/606/
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028 5 0 |a 1805  |b Henry Stewart Talks 
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100 1 |a McKeigue, Paul.  |4 spk  |9 112417 
245 1 0 |a Admixture mapping  |h [electronic resource] /  |c Paul McKeigue. 
260 |a London :  |b Henry Stewart Talks,  |c 2007. 
300 |a 1 online resource (1 streaming video file (40 min.) :  |b color, sound). 
490 1 |a Genetic epidemiology II : latest developments,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Applications of statistical modelling of population admixture -- Genetic and environmental explanations for ethnic differences in disease risk -- Methods for finding genes that influence complex traits -- Exploiting admixture to map genes -- Statistical power of admixture mapping -- Advantages of admixture mapping in comparison with other approaches to finding disease susceptibility genes -- Methodological problems of extending linkage analysis of a cross to admixed human populations -- Statistical methods that allow linkage analysis of a cross to be extended to admixed humans -- Model for stochastic variation of ancestry on chromosomes inherited from an admixed parent -- Multipoint inference of ancestry at marker loci from genotypes -- Null hypothesis as graphical model -- Statistical approach to model fitting and hypothesis testing -- The score test algorithm -- Other model diagnostics: "Bayesian p-values" -- How many markers are required for genome-wide admixture mapping? -- Panels of ancestry-informative markers -- Other applications of statistical modelling of admixture. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Genetic Predisposition to Disease  |x epidemiology.  |9 112418 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Genetic epidemiology II : latest developments.  |9 112419 
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