Chaperones and prions

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Bibliographic Details
Other Authors: Chernoff, Yury (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2020.
Series:Henry Stewart talks. Biomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi.
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Online Access:https://hstalks.com/bs/960/
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Table of Contents:
  • Contents: Prion diseases
  • Prions as self-propagating amyloids
  • Yeast prions as protein-based heritable elements
  • Prion detection
  • Crucial role of the chaperone protein Hsp104 in the propagation of yeast prions
  • Chaperone-mediated fragmentation turns amyloids into infectious or heritable prions
  • Effects of the Hsp70 and Hsp40 proteins on yeast prions
  • Other modulators of prion formation and propagation: cytoskeleton and ubiquitin system.