The structural basis for how the large ribosomal subunit catalyses peptide bond formation

The structural basis for how the large ribosomal subunit catalyses peptide bond formation

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Bibliographic Details
Other Authors: Steitz, Thomas A. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2008.
Series:Henry Stewart talks. Biomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis.
Subjects:
Protein Biosynthesis.
Ribosomal Proteins.
Ribosomes.
Online Access:https://hstalks.com/bs/802/
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Table of Contents:
  • Contents: Overview of protein synthesis by the ribosome
  • Nature of the polypeptide exit tunnel in the large subunit
  • The ribosome is a ribozyme
  • Substrate induced fit at the peptidyl transferase center
  • Proton shuttle mechanism and transition state stabilization
  • Substrate interactions at the large subunit E-site
  • Movie of the peptidyl transferase reaction.

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