Glycoprotein maturation and quality control in the endoplasmic reticulum
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Endoplasmic reticulum : fundamentals and role in disease.
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Subjects: | |
Online Access: | https://hstalks.com/bs/98/ Series |
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Table of Contents:
- Contents: Protein maturation in the secretory pathway
- ER glycoforms
- The glyco-code of the ER
- Calnexin and calreticulin
- Cotranslational folding
- Influenza hemagglutinin
- Oxidation of HA
- HA truncations
- Type I membrane proteins
- Disease states involving ER folding and quality control
- Structural determinants that cause retention
- ER retention signals
- Calnexin binding cycle
- GT or UDP glucose glycoprotein: glycosyltransferase
- Degradation of misfolded proteins
- Carbohydrate trimming
- EDEM1 functions.