Possible roles of mitochondrial biogenesis in aging

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Bibliographic Details
Other Authors: De Grey, Aubrey D. N. J., 1963- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Mitochondrial biogenesis : processes, regulation, functions and disease.
Subjects:
Online Access:https://hstalks.com/bs/180/
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Table of Contents:
  • Contents: Oxidative phosphorylation
  • The mitochondrial DNA
  • Aging as the accumulation of damage
  • Types of aging damage
  • Types of damaged cells
  • Survival of cells lacking oxidative phosphorylation
  • The plasma membrane redox system
  • Reductive hotspot hypothesis
  • "Survival of the slowest" hypothesis
  • Allotopic expression
  • Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins
  • Ways to make these proteins allotopically expressible.