Molecular identification of the CRAC channel
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| Other Authors: | |
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| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2007.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Calcium signaling I.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/403/ Series |
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Table of Contents:
- Contents: Background on Calcium signaling and ion channels in the immune system, role of CRAC channels in lymphocyte activation
- Discovery of Stim and STIM1 by RNA interference screen in Drosophila S2 cells
- Stim as an ER Calcium sensor and as a messenger to the plasma membrane
- Genome-wide RNA interference screen and the discovery of Orai
- Amplifying CRAC current by co-expression of Stim and Orai
- Molecular identification of CRAC channels by altered ion selectivity in a mutant of Orai
- How does the CRAC channel activate?
Voltage-dependent calcium channels