Modifications of pyruvate handling in health and disease

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Bibliographic Details
Other Authors: Sugden, Mary (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein epidemiology.
Subjects:
Online Access:https://hstalks.com/bs/45/
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Table of Contents:
  • Contents: Potential metabolic fates of pyruvate
  • Lactate transport
  • Role of pyruvate dehydrogenase complex (PDC)
  • Regulation of PDC
  • Mechanisms of activation of PDC by pyruvate dehydrogenase phosphatases
  • Pyruvate dehydrogenase kinase (PDK) expression and regulation
  • Multi-site phosphorylation
  • Transcription factors regulating PDK4 expression
  • Anaplerosis and cataplerosis
  • Pyruvate carboxylase
  • Insulin secretion and action
  • Glucose/fatty-acid cycle
  • Consequences of PDK4 upregulation
  • Disorders of pyruvate handling.