Protein folding and misfolding from theory to therapy /
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Other Authors: | |
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Protein folding, aggregation and design : concepts, experiments, theories and mechanisms.
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Subjects: | |
Online Access: | https://hstalks.com/bs/429/ Series |
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MARC
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008 | 080121s2007 enk|||||||||||s|||v|eng d | ||
028 | 5 | 0 | |a 1206 |b Henry Stewart Talks |
035 | |a (UkLoHST)429 | ||
035 | |a (UkLU-K)AC000392421 | ||
040 | |a UkLU-K |b eng |c UkLU-K | ||
100 | 1 | |a Dobson, C. M. |q (Christopher M.) |4 spk |9 110452 | |
245 | 1 | 0 | |a Protein folding and misfolding |h [electronic resource] : |b from theory to therapy / |c Christopher M. Dobson. |
260 | |a London : |b Henry Stewart Talks, |c 2007. | ||
300 | |a 1 online resource (1 streaming video file (69 min.) : |b color, sound). | ||
490 | 1 | |a Protein folding, aggregation and design : concepts, experiments, theories and mechanisms, |x 2056-452X | |
500 | |a Animated audio-visual presentation with synchronized narration. | ||
500 | |a Title from title frames. | ||
505 | 0 | |a Contents: Protein nature, folding and complexity -- Folding in a cellular environment -- The underlying principles of folding -- Native and transition states -- Exploring the energy surface -- The folding of lysozyme -- The consequences of protein misfolding -- The relationship between folding and disease -- Protein deposition diseases -- Protein aggregates in amyloid diseases -- Amyloidogenic mutations of lysozyme -- Mechanism of amyloid formation -- Structure of the amyloidogenic intermediate -- Amyloid formation by lysozyme in vivo -- SH3 domain of PI3 kinase -- Model of an amyloid fibril -- The underlying origins of amyloid disease -- Generic toxicity of amyloid aggregates -- Cellular defences against aggregation -- Evolutionary design of proteins -- "Post-evolutionary" diseases. | |
506 | |a Access restricted to subscribers. | ||
538 | |a Mode of access: World Wide Web. | ||
650 | 2 | |a Protein Conformation. |9 110453 | |
650 | 2 | |a Protein Folding. |9 110454 | |
650 | 2 | |a Proteins. |9 110455 | |
830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p Protein folding, aggregation and design : concepts, experiments, theories and mechanisms. |9 110456 | |
856 | 4 | 0 | |u https://hstalks.com/bs/429/ |
856 | 4 | 2 | |u https://hstalks.com/bs/p/34/ |3 Series |
999 | |c 215917 |d 215916 |