Polyadenylation of mRNA precursors mechanism, regulation and connections with other cellular processes /

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Bibliographic Details
Other Authors: Manley, James L. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.
Subjects:
Online Access:https://hstalks.com/bs/627/
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028 5 0 |a 1189  |b Henry Stewart Talks 
035 |a (UkLoHST)627 
040 |a UkLoHST  |b eng  |c UkLoHST 
100 1 |a Manley, James L.,  |u (Columbia University, USA)  |4 spk  |9 97771 
245 1 0 |a Polyadenylation of mRNA precursors  |h [electronic resource] :  |b mechanism, regulation and connections with other cellular processes /  |c James L. Manley. 
260 |a London :  |b Henry Stewart Talks,  |c 2007. 
300 |a 1 online resource (1 streaming video file (47 min.) :  |b color, sound). 
490 1 |a From DNA to proteins : the multiple levels of regulation,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Polyadenylation of mRNA precursors -- The polyadenylation machinery -- A surprising complexity in PAP -- Hyperphosphorylation by MPF inhibits PAP activity -- Gld-2 in cytoplasmic polyadenylation in oocytes -- The polyadenylation machinery -- CPSF-73 is the 3' processing endonuclease -- CPSF-73 is absent in cytoplasmic polyadenylation -- CstF protein interactions -- Regulation of gene expression by alternative polyadenylation -- The C-terminal domain of RNAPII -- The CTD can stimulate 3' cleavage in vitro -- CPSF links transcription and 3' end formation -- RNA15 crosslinks to promoters -- Polyadenylation and links to other cellular processes -- CstF-50 -- BRCA1 -- BARD1 -- BRCA associated ring domain protein -- Why does BARD1 inhibit 3' processing? -- DNA damage inhibits 3' processing -- How does BARD1 inhibit 3' processing? -- BRCA1/BARD1 target RNAPII for ubiquitination -- Many factors constitute the mRNA 3' end formation machinery. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 0 |a Gene expression.  |9 97772 
650 0 |a Genetic regulation.  |9 97773 
650 0 |a Messenger RNA.  |9 97774 
650 0 |a Polyadenylation.  |9 97775 
650 2 |a BARD1 protein, human.  |9 97776 
650 2 |a Cleavage Stimulation Factor.  |9 97777 
650 2 |a DNA Damage.  |9 97778 
650 2 |a Endonucleases.  |9 97779 
650 2 |a Gene Expression Regulation.  |9 97780 
650 2 |a Oocytes.  |9 97781 
650 2 |a Polyadenylation  |9 97782 
650 2 |a RNA Polymerase II.  |9 97783 
650 2 |a RNA Precursors.  |9 97784 
650 2 |a RNA, Messenger.  |9 97785 
650 2 |a Transcription Factors.  |9 97786 
650 2 |a Transcription, Genetic.  |9 97787 
650 2 |a Ubiquitination.  |9 97788 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p From DNA to proteins : the multiple levels of regulation.  |9 97789 
856 4 0 |u https://hstalks.com/bs/627/ 
856 4 2 |u https://hstalks.com/bs/p/22/  |3 Series 
999 |c 214663  |d 214662