Biomarkers of exposure

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Bibliographic Details
Other Authors: Smith, Thomas J. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks.
Subjects:
Online Access:https://hstalks.com/bs/84/
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Table of Contents:
  • Contents: Biomarkers as indicators of exposure, adverse effects or susceptibility for an individual
  • Methods of exposure: inhalation, ingestion or skin absorption
  • Toxicokinetics as a guide to understanding biomarker behaviour
  • Calibration of biomarkers
  • Example of using biomarkers for exposure to MTBE in gasoline
  • Using a physiologically based toxicokinetic (PBTK) model of MTBE to estimate tissue and biomarker levels
  • Metabolic gene-environment interaction in biomarker production
  • Using lab exposures to study biomarkers and the dose-response relationship.