Novel proteins from designed combinatorial libraries
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| Other Authors: | |
|---|---|
| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2007.
|
| Series: | Henry Stewart talks. Biomedical & life sciences collection. Protein folding, aggregation and design : concepts, experiments, theories and mechanisms.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/443/ Series |
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| 007 | vz|czazum | ||
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| 028 | 5 | 0 | |a 1069 |b Henry Stewart Talks |
| 035 | |a (UkLoHST)443 | ||
| 035 | |a (UkLU-K)AC000390261 | ||
| 040 | |a UkLU-K |b eng |c UkLU-K | ||
| 100 | 1 | |a Hecht, Michael H. |4 spk |9 109834 | |
| 245 | 1 | 0 | |a Novel proteins from designed combinatorial libraries |h [electronic resource] / |c Michael H. Hecht. |
| 260 | |a London : |b Henry Stewart Talks, |c 2007. | ||
| 300 | |a 1 online resource (1 streaming video file (49 min.) : |b color, sound). | ||
| 490 | 1 | |a Protein folding, aggregation and design : concepts, experiments, theories and mechanisms, |x 2056-452X | |
| 500 | |a Animated audio-visual presentation with synchronized narration. | ||
| 500 | |a Title from title frames. | ||
| 505 | 0 | |a Contents: Novel proteins can be devised using either rational/computational approaches or random/combinatorial methods -- Description of a hybrid approach that combines rational and combinatorial methods: libraries of novel proteins -- Combinatorial diversity -- Random vs. focused libraries -- Amphiphilic alpha-helices and beta-strands -- Binary patterning of polar and non-polar amino acids -- Genetic encoding of combinatorial mixtures of polar and non-polar amino acids -- Design of libraries of novel 4-helix bundles -- Library construction and expression in vivo -- Dynamic vs. wellordered protein structures -- Second generation libraries -- Biophysical characterization -- Solution structure of native-like 4-helix bundle proteins from designed libraries -- Functionally active proteins including cofactor binding proteins, peroxidases and esterases -- Designed libraries of beta sheet proteins: amyloid-like fibrils, monomeric beta-sheet proteins and novel biomaterials. | |
| 506 | |a Access restricted to subscribers. | ||
| 538 | |a Mode of access: World Wide Web. | ||
| 650 | 2 | |a Protein Conformation. |9 109835 | |
| 650 | 2 | |a Protein Engineering. |9 109836 | |
| 650 | 2 | |a Protein Folding. |9 109837 | |
| 650 | 2 | |a Proteins. |9 109838 | |
| 830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p Protein folding, aggregation and design : concepts, experiments, theories and mechanisms. |9 109839 | |
| 856 | 4 | 0 | |u https://hstalks.com/bs/443/ |
| 856 | 4 | 2 | |u https://hstalks.com/bs/p/34/ |3 Series |
| 999 | |c 215820 |d 215819 | ||
Novel proteins from designed combinatorial libraries