Protein folding inside the cell macromolecular crowding and protein aggregation /

Protein folding inside the cell macromolecular crowding and protein aggregation /

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Bibliographic Details
Other Authors: Ellis, R. J. (Reginald John), 1935- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein folding, aggregation and design : concepts, experiments, theories and mechanisms.
Subjects:
Macromolecular Substances.
Molecular Chaperones.
Protein Conformation.
Protein Folding.
Proteins.
Online Access:https://hstalks.com/bs/438/
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Table of Contents:
  • Contents: The principle of protein self-assembly
  • Discovery of proteins binding to newly synthesized polypeptides
  • Discovery of the chaperonins
  • Origins of the molecular chaperone concept
  • Replacement of spontaneous self-assembly by assisted self-assembly
  • Protein aggregation as a universal cellular problem
  • Macromolecular crowding and its effects on reaction rates and association constants
  • Stimulation of aggregation by crowding
  • How chaperones combat aggregation
  • Definition of molecular chaperones
  • The chaperone function.

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