Nano-enabled medical applications /

Nano-enabled medical applications /

This book is the second in a series presenting articles that received the most citations in recent years in nanomedicine. The series is edited by, a prominent nanotechnology researcher and editor-in-chief of Precision Nanomedicine. The theme of the second volume is about nano-enabled medical applica...

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Bibliographic Details
Other Authors: Balogh, Lajos P. (Editor)
Format: Electronic eBook
Language:English
Published: Singapore : Jenny Stanford Publishing Pte. Ltd., [2021]
Series:Nanomedicine's most cited ; volume 2
Subjects:
Nanomedicine.
MEDICAL / Biotechnology
SCIENCE / Biotechnology
Online Access:Taylor & Francis
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Table of Contents:
  • Cover
  • Half Title
  • Series Page
  • Title Page
  • Copyright Page
  • Contents
  • Preface
  • 1 Intelligent Nanomaterials for Medicine: Carrier Platforms and Targeting Strategies-State of the Art
  • 1.1 Introduction
  • 1.2 Nanotechnology Carrier Platforms Suited for Switch Functionality
  • 1.2.1 Micelles and Liposomes
  • 1.2.2 Polymeric Systems
  • 1.2.3 Dendrimers
  • 1.2.4 Carbon Nanotubes
  • 1.2.5 Metallic Nanoparticles
  • 1.2.6 Other Organic Nanoparticles: Carbohydrate-Based NPs, e.g., Chitosan and Starch
  • 1.2.7 Quantum Dots and Carbon Quantum Dots
  • 1.2.8 Nanogels
  • 1.2.9 Peptide-Based Nanoparticles as Delivery System
  • 1.3 Advanced Functionality Including Internal and External Stimuli-Responsiveness
  • 1.4 Engineering Cell and Tissue Interaction at the Nanoscale
  • 1.4.1 Targeting Strategies
  • 1.4.1.1 Passive targeting
  • 1.4.1.2 Active targeting
  • 1.4.2 Endocytotic Cellular Uptake
  • 1.4.3 Cellular Uptake by Cell-Penetrating Peptides
  • 1.4.4 Endosomal Escape
  • 1.4.5 Exocytosis
  • 1.5 Clinical Application of Nanomaterials
  • 1.5.1 The Clinical Trial Landscape: An Emphasis on Cancer
  • 1.5.2 Potential Risk Factors Regarding Approved Nanoparticle-Based Therapies
  • 1.6 Conclusions and Outlook
  • 2 Nanocarriers as an Emerging Platform for Cancer Therapy
  • 2.1 Passive and Active Targeting
  • 2.2 Types of Targeting Agents
  • 2.3 The Arsenal of Nanocarriers
  • 2.4 The Challenges of Multidrug Resistance
  • 2.5 Into the Future
  • 3 Microfluidic Technologies for Accelerating the Clinical Translation of Nanoparticles
  • 3.1 Well-Controlled Synthesis of Nanoparticles
  • 3.2 Evaluation and Screening of Nanoparticles
  • 3.3 Future Prospects
  • 4 Theranostic Nanomedicine
  • 4.1 Introduction
  • 4.2 Imaging Drug Delivery
  • 4.3 Imaging Drug Release
  • 4.4 Imaging Drug Efficacy
  • 4.5 Conclusions
  • 5 The Emerging Field of RNA Nanotechnology
  • 5.1 Significance and Uniqueness of RNA Nanotechnology
  • 5.2 Distinct Attributes of RNA inside the Body
  • 5.3 Techniques for Constructing RNA Nanoparticles
  • 5.4 Applications of RNA Nanotechnology
  • 5.5 Challenges and Perspectives
  • 6 Drug Targeting to Tumors: Principles, Pitfalls and (Pre-) Clinical Progress
  • 6.1 Introduction
  • 6.2 Principles of Drug Targeting to Tumors
  • 6.2.1 Passive Targeting
  • 6.2.2 Active Targeting to Cancer Cells
  • 6.2.3 Active Targeting to Endothelial Cells
  • 6.2.4 Triggered Drug Delivery
  • 6.3 Pitfalls in Drug Targeting to Tumors
  • 6.3.1 Extravasation and the EPR Effect
  • 6.3.2 Penetration
  • 6.3.3 Active Targeting
  • 6.3.4 Formulation
  • 6.3.5 Efficacy vs. Toxicity
  • 6.3.6 Metastasis
  • 6.3.7 Personalization
  • 6.3.8 Translation
  • 6.4 (Pre-) Clinical Progress
  • 6.5 Conclusion
  • 7 Biomolecular Coronas Provide the Biological Identity of Nanosized Materials
  • 7.1 Nanoscale Engagement with Biological Processes

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